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产品总数：60957
| 中文名称 |
Ditiocarb sodium
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| 中文别名 |
二乙基二硫代氨基甲酸钠;二乙基二硫代氨基甲酸钠盐;铜试剂;二乙胺荒酸钠;DDTC钠盐;二乙基二硫代氨基甲酸钠盐(三水);二硫拉唑;二硫卡钠;二硫碳钠;二乙基二硫代氨基甲酸钠(铜试剂);(铜试剂)二乙基二硫代氨基甲酸钠;(铜试剂)二乙基二硫代氨基甲酸钠,AR;2-氨基-5-硝基苯甲酰胺;4-溴-2,5-二氟碘苯;N,N-二乙二硫胺甲酸钠三水合物;二乙基二硫代氨基甲酸钠(铜试剂),DDTC钠盐;二乙基二硫代氨基甲酸钠三水合物;N,N-二乙基二硫代氨基甲酸钠 标准品;二乙基二硫代氨基甲酸钠,DDTC钠盐;二乙基二硫代氨基甲酸钠,三水;二乙基二硫代氨基甲酸钠试液（药典）,Sodium diethyldithiocarbamate;橡胶促进剂SDEC;乙硫氮
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| 英文名称 |
Ditiocarb sodium
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| 英文别名 |
DIETHYLDITHIOCARBAMIC ACID SODIUM SALT;N,N-DIETHYLDITHIOCARBAMIC ACID, NA;SDEC;Carbamodithioicacid,diethyl,sodiumsalt;dedc;dedk;diethylcarbamodithioicacid,sodiumsalt;diethyl-carbamodithioicacisodiumsalt;diethyldithiocarbamatesodium;diethyldithiocarbamicacidsodium;diethyldithio-carbamicacisodiumsalt;diethylsodiumdithiocarbamate;dithiocarbamate;ditiocarbsodium;imuthiol;kupral;n,n-diethyldithiocarbamicacid,sodiumsalt;na-ddtc;Dithiocarb;Sodium Diethyldithio;Sodium diethyldithiocarbamate;Sodium Diethyldithiocarbamate
Discontinued See D444270 (the trihydrate);Sodium DiethyldithiocarbamateDiscontinued See D444270 (the trihydrate);sodium,N,N-diethylcarbamodithioate;Sodium N,N-diethyldithiocarbamate;DTC;DDTC;NADEDC;thiocarb;Ditiocarb sodium;Sodium diethylcarbamodithioate;Cupral;Nocceler SDC;Soxinol ESL;Carbamodithioic acid, diethyl-, sodium salt;Sodium DEDT;Diethyldithiocarbamic acid, sodium salt;A5304YEB5E;Ditiocarb sodium [INN];sodium N,N-diethylcarbamodithioate;Diethyldithiocarbamate sodium;Ditiocarbe sodique [French];Ditiocarbo sodico [Spanish];D
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| Cas No. |
148-18-5
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| 分子式 |
C5H10NNaS2
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| 分子量 |
171.26
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| 包装储存 |
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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| 产品详情 |
Ditiocarb sodium (Sodium diethyldithiocarbamate) 是一种铜试剂，与 Cu2+ 溶液反应，生成络合物，提高了铜置换沉淀速率。Sodium diethyldithiocarbamate 可降低 HIV 感染，并应用于高危乳腺癌的辅助免疫治疗。
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| 生物活性 |
Ditiocarb sodium (Sodium diethyldithiocarbamate) is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection, and also enhances adjuvant immunotherapy of high risk breast cancer.
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| 性状 |
Solid
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| IC50 & Target[1][2] |
HIV
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| 体外研究(In Vitro) |
Ditiocarb sodium (Sodium diethyldithiocarbamate) reacts with the Cu solution giving a complex of copper diethyldithiocarbamate, which enhances the rate of cementation. Ditiocarb sodium is an agent with strong antioxidant capacity and chelating activities. has not independently confirmed the accuracy of these methods. They are for reference only.
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| 体内研究(In Vivo) |
Ditiocarb sodium (Sodium diethyldithiocarbamate) improves the depressed immune responses of newborn and aged mice. Sodium diethyldithiocarbamate prevents cisplatin nephrotoxicity in animals without reducing the antitumor activity. In that AIDS model, Ditiocarb sodium reduces lymphadenopathy and hypergammaglobulinemia, restores immunocompetence, and prolongs survival. has not independently confirmed the accuracy of these methods. They are for reference only.
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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| ClinicalTrial |
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| 参考文献 |
[1]. Abeer A.El-Saharty, et al. Sodium diethyldithiocarbamate as accelerator of the rate of copper cementation. The Egyptian Journal of Aquatic Research. 2015 Dec, Volume 41(4):289-293.[2]. Hersh EM, et al. Ditiocarb sodium (diethyldithiocarbamate) therapy in patients with symptomatic HIV infection and AIDS. A randomized, double-blind, placebo-controlled, multicenter study. JAMA. 1991 Mar 27;265(12):1538-44.
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| 溶解度数据 |
In Vitro: DMSO : 100 mg/mL (583.91 mM; Need ultrasonic)配制储备液
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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。
2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。
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