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AKT Kinase Inhibitor hydrochloride

目录号: PL01358 纯度: ≥99%

AKT Kinase Inhibitor hydrochloride 是一种具有抗肿瘤活性的 Akt 抑制剂。

商品编号	规格	价格	会员价
PL01358-5mg	5mg	¥5625.00	请登录
PL01358-10mg	10mg	¥9643.00	请登录
PL01358-25mg	25mg	¥20251.00	请登录
PL01358-50mg	50mg	询价	询价
PL01358-100mg	100mg	询价	询价

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中文名称	AKT Kinase Inhibitor hydrochloride
英文名称	AKT Kinase Inhibitor hydrochloride
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
详情描述	AKT Kinase Inhibitor hydrochloride 是一种具有抗肿瘤活性的 Akt 抑制剂。

产品详情	AKT Kinase Inhibitor hydrochloride 是一种具有抗肿瘤活性的 Akt 抑制剂。
生物活性	AKT Kinase Inhibitor hydrochloride is an Akt kinase inhibitor with anti-tumor activity.
性状	Solid
体外研究(In Vitro)	The effect of selective inhibition of Akt in proliferating cells expressing Trop-2 is studied. Akt inhibition, either by silencing or with specific drugs, induces a marked decrease in cell proliferation in cells expressing Trop-2, in a dose-dependent fashion. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Saverio Alberti, et al. Use of trop-2 as predictive marker of response to anti-tumor therapy based on inhibitors of cd9, akt and molecules of the tetraspanin signalling network. WO2013171777A2.

溶解度数据	In Vitro: DMSO : 3.33 mg/mL (8.46 mM; ultrasonic and warming and heat to 60°C)配制储备液

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Data Sheet

[1]. Saverio Alberti, et al. Use of trop-2 as predictive marker of response to anti-tumor therapy based on inhibitors of cd9, akt and molecules of the tetraspanin signalling network. WO2013171777A2.

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

AKT Kinase Inhibitor hydrochloride

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