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L-Histidine

(Synonyms: L-组氨酸)

目录号: PC57512 纯度: ≥99%

L-Histidine 是婴儿必需的氨基酸。L-Histidine 是线粒体谷氨酰胺转运的抑制剂。L-Histidine 是婴儿必需的氨基酸。L-Histidine 是线粒体谷氨酰胺转运的抑制剂。

CAS No. :71-00-1

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中文名称	L-Histidine
中文别名	L-组氨酸;L-A-氨基-β-4-咪唑基丙酸;(S)-2-氨基-3-(4-咪唑基)丙酸;组氨酸;L-组织氨基酸;Α-氨基-1H-咪唑-4-丙酸;咪唑-5-Α-丙氨酸;L-Histidine; L-组氨酸;L-组氨酸 USP标准品;L-组氨酸标准品;L-组氨酸(RG);L-组氨酸（碱）;L-组氨酸,BR;L-组氨酸,对照品;L-组氨酸碱;L-组氨酸盐酸盐;组氨酸 EP标准品;2-胺-3-咪唑丙酸;L-2-氨基-3(4-咪唑基)丙酸;L-α-氨基-β-4-咪唑基丙酸;L-组氨酸,L-Histidine,EP, USP ,非动物源,用于细胞培养;織胺酸;组氨酸杂质标准品
英文名称	L-Histidine
英文别名	L-Histidine;L-Histidine,free base;(S)-2-Amino-3-(4-imidazolyl)propionic acid~H-His-OH;L-Histidine Base;H-His-OH;L-Hisidine;CultureSure L-Histidine, Animal-derived-free;Histidine;HISTIDINE, L-(P);HISTIDINE, L-(RG);L-[+]-Histidine;L-HISTIDINE AJI 92;d,l-histidine;FEMA 3694;Histidin;H-L-HIS-OH;L-HIS;L-Histdine;NSC 137773;L-2-Amino-3-(4-imidazolyl)propionic acid;glyoxaline-5-alanine;Anti-rheuma;L-(-)-Histidine;Istidina;S-Histidine;(L)-Histidine;Histidine (VAN);histidina;(S)-4-(2-Amino-2-carboxyethyl)imidazole;Histidinum;(2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid;L-Histidin;(S)-alpha-amino-1H-imidazole-4-propanoic acid;HISTIDINE, L-;Histidinum [INN-Latin];Histidine [USAN:INN];(S)-Histidine;Histidina [INN-Spanish];L-beta-(4-Imidazolyl)alanin;4-(2-Amino-2-carboxyethyl)imidazole;1H-Imidazole-4-alanine,
Cas No.	71-00-1
分子式	C₆H₉N₃O₂
分子量	155.15
包装储存	Powder； -20°C； 3 years; 4°C； 2 years；
详情描述	L-Histidine 是婴儿必需的氨基酸。L-Histidine 是线粒体谷氨酰胺转运的抑制剂。L-Histidine 是婴儿必需的氨基酸。L-Histidine 是线粒体谷氨酰胺转运的抑制剂。

生物活性

L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.

性状

Solid

IC50 & Target[1][2]

Human Endogenous Metabolite
Microbial Metabolite

体外研究(In Vitro)

L-histidine completely inhibits growth and its effect on viability is inversely related to FLO11 expression. L-histidine does not affect the viability of the Δflo11 and S288c strains. L-histidine dramatically decreases air-liquid biofilm formation and adhesion to polystyrene of the flor yeasts with no effect on the transcription level of the FLO11 gene. Moreover, L-histidine modifies the chitin and glycans content on the cell-wall of flor yeasts.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究(In Vivo)

L-histidine (100 mg/kg) completely inhibits the brain edema in thioacetamide-treated rats. Histamine release stimulated by high K from the hypothalamus in the L-histidine diet group is 60% of that in the control group. However, the concentrations of other monoamines and their metabolites are not changed by the L-histidine diet. The open-field tests show that the L-histidine diet group spends a shorter amount of time in the central zone, and the light/dark box tests demonstrate that the L-histidine diet group spends a shorter amount of time in the light box, suggesting that the L-histidine diet induced anxiety-like behaviors.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature or refrigerated transport.

储存方式

Powder； -20°C； 3 years; 4°C； 2 years；

ClinicalTrial

结构分类

Amino acids

溶解度数据	体外研究: H₂O : 20.83 mg/mL(134.26 mM;ultrasonic and warming and heat to 80°C) DMSO : 1 mg/mL(6.45 mM;ultrasonic and warming and heat to 80°C)

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产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

L-Histidine

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