Rentiapril racemate|72679-47-1|(SA-446 racemate)-陌孚医药/Medlife

您当前的位置：

Rentiapril racemate (Synonyms: SA-446 racemate)

目录号: PL14772 纯度: ≥98%

CAS No. :72679-47-1

商品编号	规格	价格	会员价
PL14772-1mg	1mg	¥7714.00	请登录
PL14772-5mg	5mg	¥16876.00	请登录
PL14772-10mg	10mg	询价	询价
PL14772-50mg	50mg	询价	询价

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Rentiapril racemate
中文别名	伦唑普利外消旋体;伦噻普利外消旋体
英文名称	Rentiapril racemate
英文别名	rentiapril;Rentiapril (racemate);(4R)-2-(2-hydroxyphenyl)-3-(3-mercaptopropanoyl)-4-thiazolidinecarboxylic acid;2-(2'-Hydroxyphenyl)-3-(3-mercaptopropanoyl)-4-thiazolidine carboxylic acid;4-Thiazolidinecarboxylic acid, 2-(2-hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)-;AC1L3TZY;AC1Q5JZ5;AGN-PC-00KHP0;C13H15NO4S2;CHEMBL110444;SA 446;SA-446;2-(2-hydroxyphenyl)-3-(3-sulfanylpropanoyl)-1,3-thiazolidine-4-carboxylic acid;2-(2-hydroxyphenyl)-3-(3-mercaptopropanoyl)thiazolidine-4-carboxylic acid;Rentiapril racemate;2-(2-Hydroxyphenyl)-3-(3-mercapt
Cas No.	72679-47-1
分子式	C₁₃H₁₅NO₄S₂
分子量	313.39
包装储存	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

产品详情	Rentiapril racemate (SA-446 racemate) 是 Rentiapril 的外消旋体。Rentiapril 是一种血管紧张素转换酶 (ACE) 抑制剂。
生物活性	Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril. Rentiapril is an angiotensin converting enzyme (ACE) inhibitor.
性状	Solid
IC50 & Target[1][2]	Angiotensin converting enzyme (ACE)
体内研究(In Vivo)	A three-months toxicity study of an angiotensin converting enzyme (ACE) inhibitor, Rentiapril (CAS 80830-42-8), is performed in Sprague-Dawley rats by oral administration. The dose levels of 0, 30, 125, 500 and 1000 mg/kg are tested in both sexes, in which each experimental group comprised 10 rats. Another ACE inhibitor, captopril, is used as a reference compound. Rentiapril at the highest dose of 1000 mg/kg causes low food consumption and death of some animals with signs of bloody feces and anemia. In males and females receiving 500 and 1000 mg/kg, there are low body weight gain, increases in water intake, urine volume and serum BUN level, and decreases in levels of various erythrocytic parameters. Kidney weight is increased dose-dependently in both sexes. Histopathologically, renal changes in the 500 and 1000 mg/kg groups consist of proximal tubular degeneration, juxtaglomer
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献	[1]. Takase K, et al. Toxicity study of the angiotensin converting enzyme inhibitor rentiapril in rats. Arzneimittelforschung. 1995 Jan;45(1):15-8.

溶解度数据	In Vitro: DMSO : 100 mg/mL (319.09 mM; Need ultrasonic)配制储备液

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation