Pivalopril|81045-50-3|(匹伏普利; Pivopril; RHC 3659(S))-陌孚医药/Medlife

您当前的位置：

Pivalopril (Synonyms: 匹伏普利; Pivopril; RHC 3659(S))

目录号: PL14774 纯度: ≥99%

CAS No. :81045-50-3

商品编号	规格	价格	会员价
PL14774-5mg	5mg	¥8197.00	请登录
PL14774-10mg	10mg	¥13179.00	请登录
PL14774-50mg	50mg	询价	询价
PL14774-100mg	100mg	询价	询价

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Pivalopril
中文别名	匹伏普利
英文名称	Pivalopril
英文别名	Pivopril;(S)-N-cyclopentyl-N-[3-[(2,2-dimethyl-1-oxopropyl)thio]-2-methyl-1-oxopropyl]glycine;RHC 3659(S);Pivalopril;3V6I5962EM;Pivopril [USAN:INN];Pivopril (USAN/INN);REV 3659(S);USV 3659(S);USV 3659-(S);RHC 3659-(S);BDBM50421708;REV 3659-(S);D03763;Q27258071;2,2-Dimethylthiopropionic acid, S-ester with (-)-(S)-N-cyclopentyl-N-(3-mercapto-2-methylpropionyl)glycine;Glycine, N-cyclopentyl-N-(3-((2,2-dimethyl-1-oxopropyl)thio)-2-methyl-1-oxopropyl)-, (S)-(-)-
Cas No.	81045-50-3
分子式	C₁₆H₂₇NO₄S
分子量	329.45
包装储存	Powder -20°C 3 years；4°C 2 years

产品详情	Pivalopril 是一种新的口服活性的血管紧张素转换酶 (ACE) 抑制剂。
生物活性	Pivalopril is a new orally active angiotensin converting enzyme (ACE) inhibitor.
性状	Solid
IC50 & Target[1][2]	ACE
体内研究(In Vivo)	Pivalopril is a new compound with a hindered sulfur group that has been compared to Captopril for oral angiotensin-converting enzyme (ACE) inhibition in rats and dogs and antihypertensive activity in rats. In separate groups of conscious normotensive rats, Pivalopril (0.03-1.0 mg/kg, orally [p.o.]) produces a dose-related antagonism of angiotensin I (AngI)-induced pressor effects. The ED 50 for Pivalopril and Captopril is 0.1 mg/kg. In conscious normotensive dogs, Pivalopril (incremental doses of 0.01-1.0 mg/kg, p.o.) produces a dose-related antagonism of AngI pressor effects. The ED 50 is 0.17 mg/kg for Pivalopril and 0.06 mg/kg for Captopril. At equieffective doses the two compounds have similar durations of action. In sodium-deficient, conscious spontaneously hypertensive rats (SHR), Pivalopril (1-100 mg/kg, p.o.) produces a dose-related reduction in mea
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Powder -20°C 3 years；4°C 2 years
参考文献	[1]. Burnier M, et al. RHC 3659: a new orally active angiotensin converting enzyme inhibitor in normal volunteers. Br J Clin Pharmacol. 1981 Dec;12(6):893-9. [2]. Wolf PS, et al. Angiotensin-converting enzyme inhibitory and antihypertensive activities of pivalopril (RHC 3659-(S)). Fed Proc. 1984 Apr;43(5):1322-5.

溶解度数据	In Vitro: DMSO : 90 mg/mL (273.18 mM; Need ultrasonic)配制储备液

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation