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Sulfobromophthalein disodium salt

目录号: PL14164 纯度: ≥98.0%

Sulfobromophthalein (Bromosulfophthalein) disodium salt 是一种有机阴离子染料，用于研究动物组织中表达的多种膜载体，并参与药物和代谢物的运输。

CAS No. :71-67-0

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中文名称	Sulfobromophthalein disodium salt
中文别名	四溴磺酚钠;磺溴酚酞钠;对甲苯磺酰基H酸;磺溴酚酞钠盐水合物;磺溴酞钠
英文名称	Sulfobromophthalein disodium salt
英文别名	Sulfobromophthalein sodium tetrahydrate;Bromosulfalein;Sulfobromophthalein sodium salt hydrate;disodium 6,6-dihydroxy-3,3-(4,5,6,7-tetrabromo-1,3-dihydro-3-oxoisobenzofuran-1-ylidene)dibenzenesulphonate;disodium phenoltetrabromophthaleindisulphonate;4,5,6,7-tetrabromo-3’,3’’-disulfo-phenolphthaleidisodiumsalt;benzenesulfonicacid,3,3’-(4,5,6,7-tetrabromo-3-oxo-1(3h)-isobenzofuranylidene;bromosulphthalein;bromotaleina;bromsulfalein;bromsulfan;bromsulfophthalein;BROMOSULFALEIN FOR MICROSCOPY;Bromosulfophthalein;Bromsulphalein;Bromthalein;disodium,2-hydroxy-5-[4,5,6,7-tetrabromo-1-(4-hydroxy-3-sulfonatophenyl)-3-oxo-2-benzofuran-1-yl]benzenesulfonate;Hepatosulfalein;Sodium bromosulfalein;Sodium bromosulfophthalein;Sodium bromsulphalein;Sulfobromophthalein;Sulfobromophthalein disodium salt
Cas No.	71-67-0
分子式	C₂₀H₈O₁₀S₂Br₄-₂^.₂[Na+]
分子量	838.00
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
详情描述	Sulfobromophthalein (Bromosulfophthalein) disodium salt 是一种有机阴离子染料，用于研究动物组织中表达的多种膜载体，并参与药物和代谢物的运输。

产品详情	Sulfobromophthalein (Bromosulfophthalein) disodium salt 是一种有机阴离子染料，用于研究动物组织中表达的多种膜载体，并参与药物和代谢物的运输。
生物活性	Sulfobromophthalein (Bromosulfophthalein) disodium salt is an organic anion dye used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of drugs and metabolites.
性状	Solid
体外研究(In Vitro)	Sulfobromophthalein disodium salt is a synthetic dye introduced in 1925 as a clinical tool aiming at the assessment of the liver function. Sulfobromophthalein (BSP) is a pH indicator dye, featured by fast (17), protondependent quinoidal–phenolic tautomerism (pK = 8.5) . Bromosulfalein has been commonly used as both a substrate and inhibitor of organic anionic transporting polypeptide 1B1 (OATP1B1), OATP1B3, OATP1A2, and OATP2B1, as well as multidrug resistance protein 2 (MDR2) . has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Saki Izumi, et al. Substrate-dependent inhibition of organic anion transporting polypeptide 1B1: comparative analysis with prototypical probe substrates estradiol-17β-glucuronide, estrone-3-sulfate, and sulfobromophthalein. Drug Metab Dispos. 2013 Oct;41(10):1859-66.

溶解度数据	In Vitro: DMSO : 500 mg/mL (596.66 mM; Need ultrasonic)配制储备液

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[1]. Saki Izumi, et al. Substrate-dependent inhibition of organic anion transporting polypeptide 1B1: comparative analysis with prototypical probe substrates estradiol-17β-glucuronide, estrone-3-sulfate, and sulfobromophthalein. Drug Metab Dispos. 2013 Oct;41(10):1859-66.

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

Sulfobromophthalein disodium salt

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