FHZ|1883737-63-0|-陌孚医药/Medlife

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FHZ

目录号: PL12858 纯度: ≥98%

FHZ 是一个荧光探针。

CAS No. :1883737-63-0

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中文名称	FHZ
中文别名	FHZ荧光探针;化合物 T15279
英文名称	FHZ
英文别名	2-Amino-3′-hydroxy-6′-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)spiro[isoindoline-1,9′-xanthen]-3-one;FHZ;FHZ, >=98% (HPLC);2-Amino-3'-hydroxy-6'-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)spiro[isoindoline-1,9'-xanthen]-3-one;2-Amino-3'-hydroxy-6'-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]spiro[isoindole-3,9'-xanthene]-1-one;FHZ >=98% (HPLC)
Cas No.	1883737-63-0
分子式	C₂₆H₂₆N₂O₇
分子量	478.49
包装储存	Powder -20°C 3 years；4°C 2 years

产品详情	FHZ 是一个荧光探针。
生物活性	FHZ is a fluorescent probe.
性状	Solid
体外研究(In Vitro)	After loaded with probe FHZ and treated with HClO and H2O2/EDTA-Fe in order, HeLa cells display the bright fluorescences from both cyan and green channels. FHZ can give out two different fluorescent signals in the presence of both ?OH and HClO, suggesting the synchronous discrimination of ?OH and HClO by a dual-channel detection model with two exciting wavelengths. Probe FHZ shows very high specificity to the detections of ?OH and HClO with the excitations at 410 and 490 nm, respectively. The probe FHZ can efficiently enter the cellular mitochondria and exhibit the differentiable/visual capabilities to the endogenous ?OH and HClO by the dual fluorescent responses. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	Probe FHZ can rapidly be absorbed into the blood circulation system from the zebrafish intestine, and spread out whole zebrafish tissues, and keep its stability in the blood, organs and tissues in the absence of ROS. The probe can keep its stability in biological environments and only selectively react with ?OH and HClO species. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Powder -20°C 3 years；4°C 2 years
Emission(Em)	Em 495-570 nm Green
Excitation(Ex)	Ex 450-495 nm Blue
参考文献	[1]. Zhang R, et al. Real-Time Discrimination and Versatile Profiling of Spontaneous Reactive Oxygen Species in Living Organisms with a Single Fluorescent Probe. J Am Chem Soc. 2016 Mar 23;138(11):3769-78.

溶解度数据	In Vitro: DMSO : 100 mg/mL (208.99 mM; Need ultrasonic)配制储备液

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2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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