Procion Blue HB|12236-82-7|(蓝色染料; Reactive Blue 2)-陌孚医药/Medlife

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Procion Blue HB (Synonyms: 蓝色染料; Reactive Blue 2)

目录号: PL09267

Procion Blue HB (Reactive Blue 2)是嘌呤能拮抗剂。

CAS No. :12236-82-7

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PL09267-10mM*1mLinDMSO	10mM*1mLinDMSO	¥884.00	请登录

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中文名称	Procion Blue HB
中文别名	C.I.活性蓝2;活性蓝 2;兰色染料;亚铬酸镧;汽巴蓝;汽巴蓝F3GA
英文名称	Procion Blue HB
英文别名	2-Anthracenesulfonicacid, 1-amino-4-[[4-[[4-chloro-6-[[3(or4)-sulfophenyl]amino]-1,3,5-triazin...;2-Anthracenesulfonicacid, 1-amino-4-[[4-[[4-chloro-6-[[3(or4)-sulfophenyl]amino]-1,3,5-triazin-2-yl]amino]-3-sulfophenyl]amin;Cibacron blue F3GA, C.I. 61211 (Reactive blue 2);REACTIVE BLUE 2 C.I. NO. 61211;C.I.REACTIVEBLUE2;cibacron blue;CIBACRON BLUE 3G-A;CIBRACONBLUEF3GA;Kayacion Blue A-B;PROCION BLUE HBS;procion blue hb;reactive blue 2;2-Anthracenesulfonic acid,1-amino-4-[[4-[[4-chloro-6-[[3(or 4)-sulfophenyl]amino]-1,3,5-triazin-2-yl]amino]-3-sulfophenyl]amino]-9,10-dihydro-9,10-dioxo-;Procion Blue HB
Cas No.	12236-82-7
分子式	C₂₉H₂₀N₇O₁₁S₃Cl
分子量	774.16
包装储存	4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

产品详情	Procion Blue HB (Reactive Blue 2)是嘌呤能拮抗剂。
生物活性	Procion Blue HB (Reactive Blue 2) is a purinergic antagonist.
性状	Solid
体外研究(In Vitro)	Reactive Blue 2 is used as an ATP receptor antagonist and induces Ca oscillations in HeLa cells. Reactive Blue 2 enhances a Ca response to histamine that is linked to the PLC cascade. Reactive Blue 2 may activate the PLC cascade in an extracellular Ca-dependent manner and induce Ca oscillations. The application of Reactive Blue 2 increases K secretion in a dose-dependent manner, and this increase is characterized as a peak followed by a partial relaxation to a steady-state. Reactive Blue 2 has antagonistic activities at P2Y4, and the antagonist potency at P2Y4 paralleled the potency of K+ secretion.The anthraquinone dye reactive blue 2 is found to be a potent inhibitor of a protein kinase isolated and purified from thylakoids. The mode of inhibition is noncompetitive, with a Ki of 8 μM for the membrane-bound kinase, and 6 microM for the purified kinase. The inhibito
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献	[1]. Okuda A, et al. Reactive blue 2 induces calcium oscillations in HeLa cells. Jpn J Physiol. 2001 Jun;51(3):389-93. [2]. Lee JH, et al. Reactive blue 2, an antagonist of rat P2Y4, increases K+ secretion in rat cochlea strial marginal cells. Hear Res. 2006 Sep;219(1-2):66-73. [3]. Coughlan SJ, et al. Reactive blue

溶解度数据	In Vitro: DMSO : ≥ 110 mg/mL (142.09 mM)H₂O : 10 mg/mL (12.92 mM; Need ultrasonic)Ethanol : 1 mg/mL (1.29 mM; Need ultrasonic)

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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