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6-O-Methyl Guanosine

目录号: PL07938 纯度: ≥98%

6-O-Methyl Guanosine 是一种修饰的核苷。6-O-Methyl Guanosine (6-methylguanosine) 作用于恶性着色性干皮病细胞系，抑制集落形成。

CAS No. :7803-88-5

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中文名称	6-O-Methyl Guanosine
中文别名	6-O-甲基鸟苷;6-甲氧基-鸟苷
英文名称	6-O-Methyl Guanosine
英文别名	Guanosine, 6-O-methyl-;6-O-Methyl Guanosine;(2R,3S,4R,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;2-Amino-6-methoxypurine Ribonucleoside;2-amino-6-methoxypurine riboside;6-Methoxy-6-deoxoguanosine;Guanosine,o-methyl;O6-METHYLGUANOSINE;o-methoxydeoxyguanosine;o-methyl-guanosin;O-Methylguanosine;HMS3654B03;NSC66381;2-Amino-6-methoxypurine arabinoside;Arranon (TN) (Glaxo Smith Kline);NSC686673;NSC132361;API0003528;(2R,3R,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;NS00098886;NS00002328;6-methoxy-9-pentofuranosyl-9H-purin-2-amine;9H-Purin-2-amine,6-methoxy-9-b-D-xylofuranosyl-;(2R,3S,4S,5R)-2-(2-amino-6-methoxypuri
Cas No.	7803-88-5
分子式	C₁₁H₁₅N₅O₅
分子量	297.27
包装储存	Powder -20°C 3 years；4°C 2 years
详情描述	6-O-Methyl Guanosine 是一种修饰的核苷。6-O-Methyl Guanosine (6-methylguanosine) 作用于恶性着色性干皮病细胞系，抑制集落形成。

产品详情	6-O-Methyl Guanosine 是一种修饰的核苷。6-O-Methyl Guanosine (6-methylguanosine) 作用于恶性着色性干皮病细胞系，抑制集落形成。
生物活性	6-O-Methyl Guanosine is a modified nucleoside. 6-O-Methyl Guanosine (6-methylguanosine) inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.
性状	Solid
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Powder -20°C 3 years；4°C 2 years
参考文献	[1]. Grasby JA, et al. The synthesis of oligoribonucleotides containing O6-methylguanosine: the role of conserved guanosine residues in hammerhead ribozyme cleavage. Nucleic Acids Res. 1993 Sep 25;21(19):4444-50. [2]. Thielmann HW, et al. 6-Methylguanine and 6-methylguanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line but not in other xeroderma pigmentosum and normal human fibroblast strains after treatment with 1-(2-chloroethyl)-1-nitroso-3-(2-hydroxyethyl)-urea. J Cancer Res Clin Oncol. 1987;113(1):67-72.

溶解度数据	In Vitro: DMSO : 130 mg/mL (437.31 mM; Need ultrasonic)H₂O : 2 mg/mL (6.73 mM; Need ultrasonic and warming)配制储备液

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[1]. Grasby JA, et al. The synthesis of oligoribonucleotides containing O6-methylguanosine: the role of conserved guanosine residues in hammerhead ribozyme cleavage. Nucleic Acids Res. 1993 Sep 25;21(19):4444-50.
[2]. Thielmann HW, et al. 6-Methylguanine and 6-methylguanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line but not in other xeroderma pigmentosum and normal human fibroblast strains after treatment with 1-(2-chloroethyl)-1-nitroso-3-(2-hydroxyethyl)-urea. J Cancer Res Clin Oncol. 1987;113(1):67-72.

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

6-O-Methyl Guanosine

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