HAEGTFTSD
目录号: PL05826 纯度: ≥98%
CAS No. :926018-45-3
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中文名称
HAEGTFTSD
中文别名
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-OH
英文名称
HAEGTFTSD
英文别名
HAEGTFTSD;L-Histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-aspartic acid (ACI);L;227: PN: WO2011048614 SEQID: 3 unclaimed sequence;4: PN: WO2007017892 SEQID: 3 claimed sequence;4: PN: WO2007030706 SEQID: 4 claimed sequence;7: PN: WO2012121302 SEQID: 7 unclaimed protein
Cas No.
926018-45-3
分子式
C40H57N11O17
分子量
963.94
包装储存
Sealed storage, away from moisture and lightPowder -80°C 2 years;-20°C 1 year
产品详情
HAEGTFTSD 是 GLP-1 肽或 GLP-1(7-36), amide (HY-P0054A) 的 9 个残基的肽段。GLP-1(7-36), amide 是一种生理促胰岛素激素,以葡萄糖依赖式,刺激胰岛素分泌的方式。
生物活性
HAEGTFTSD is a 9-residue peptide of human GLP-1 peptide or GLP-1(7-36), amide (HY-P0054A). GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretionin a glucose-dependant manner
性状
Solid
体外研究(In Vitro)
The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisture and lightPowder -80°C 2 years;-20°C 1 year
SequenceShortening
HAEGTFTSD
参考文献
[1]. K Hupe-Sodmann, et al. Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides. Regul Pept. 1995 Aug 22;58(3):149-56.
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2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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