U0126U0126

U0126

1,4-二氨基-2,3-二氰基-1,4-双(邻氨基苯巯基)丁二烯;5-溴-1-甲基-1H-吡唑-3-胺;荧光增白剂DT;1,4-二氨基-2,3-二氰基-1,4-双(邻氨基苯硫基)丁二烯;MEK抑制剂(U0126);(2Z,3Z)-2,3-双(氨基((2-氨基苯基)硫代)亚甲基)琥珀腈/U0126;2,3-双[氨基[(2-氨基苯基)硫代]亚甲基]-丁二腈

U0126

Butanedinitrile,2,3-bis[amino[(2-aminophenyl)thio]methylene]-;(2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanylmethylidene]butanedinitrile;U0126;U-0126;Bis[amino(o-aminophenylthio)methylene]succinonitrile;UO 126;U0126 (Uo126);1,4-DIAMINO-2,3-DICYANO-1;1,4-DIAMINO-2,3-DICYANO-1,4-BIS(2-AMINOPHYNYLTIO)BUTADIENE;2,3-Bis[amino[(2-aminophenyl)thio]methylene]butanedinitrile;1,4-DIAMINO-2,3-DICYANO-1,4-BIS(2-AMINOPHENYLTHIO)BUTADIENE;U 0126;U0126 >99%;U0126, >=98%;1,4-DIAMINO-2,3-DICYANO-1,4-BIS(O-AMINOPHENYLMERCAPTO)BUTADIENE;8027P94HLL;8027P94HLL;NCGC00025029-02;NCGC00025029-02;218601-62-8;218601-62-8;U-0126 is known as an MEK inhibitor and AMPK activator.;U-0126 is known as an MEK inhibitor and AMPK activator.;HMS3678K05;HMS3678K05;BiomolKI2_000012;BiomolKI2_000012;BCP01851;BCP01851;CS-0003351;CS-0003351;AMY31125;AMY31125;BSPBio_001224;BSPBio_001224;UNII-8027P94HLL;UNII-8027P94HLL;NCGC00025029-03;NCGC00025029-03;(2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylene}succinonitrile;(2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylene}succinonitrile;U 126;U 126;A846574;A846574;SR-01000597365;SR-01000597365;NCGC00025029-04;109511-58-2 (free);NCGC00025029-04;2,3-Bis(amino((2-aminophenyl)thio)methylene)succinonitrile;109511-58-2 (free);Succinonitrile, bis(amino(o-aminophenylthio)methylene)-;2,3-Bis(amino((2-aminophenyl)thio)methylene)succinonitrile;BMK1-B2;Succinonitrile, bis(amino(o-aminophenylthio)methylene)-;BMK1-B2;HMS1990N05;HMS1990N05;1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene;1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene;DTXSID10892034;DTXSID10892034;HMS1792N05;HMS1792N05;J-002297;J-002297;(2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylidene}butanedinitrile;(2Z,3Z)-bis({amino[(2-aminophenyl)sulfanyl]methylidene})butanedinitrile;(2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylidene}butanedinitrile;AKOS040744815;(2Z,3Z)-bis({amino[(2-aminophenyl)sulfanyl]methylidene})butanedinitrile;FT-1069-1;AKOS040744815;HMS3414K05;FT-1069-1;1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene;HMS3414K05;1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene;AKOS024456414;AKOS024456414;BRD-K18787491-001-04-5;BRD-K18787491-001-04-5;BRD-K46419649-001-01-8;BRD-K46419649-001-01-8;(2z)-Bis{amino[(2-Aminophenyl)sulfanyl]methylidene}butanedinitrile;(2z)-Bis{amino[(2-Aminophenyl)sulfanyl]methylidene}butanedinitrile;GTPL5282;Butanedinitrile, bis(amino((2-aminophenyl)thio)methylene)-;GTPL5282;1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene;Butanedinitrile, bis(amino((2-aminophenyl)thio)methylene)-;Q7863562;1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene;(2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanyl-methylene]butanedinitrile;Q7863562;(2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanyl-methylene]butanedinitrile;CHEBI:64208;(2Z,3Z)-2,3-Bis[amino[(2-aminophenyl)thio]methylene]butanedinitrile;CHEBI:64...

109511-58-2

C₁₈H₁₆N₆S₂

380.49

U0126 是一种有效的特异性非竞争性 MAP 激酶抑制剂, 抑制 MEK-1 和 MEK-2，IC50 值分别为 0.07 和 0.06 μM。 U0126 抑制自噬和线粒体自噬。