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11-Dehydrocorticosterone

目录号: PC22336

11-Dehydrocorticosterone is an endogenous mineralocorticoid.

CAS No. :72-23-1

中文名称	11-Dehydrocorticosterone
英文名称	11-Dehydrocorticosterone
Cas No.	72-23-1
详情描述	11-Dehydrocorticosterone is an endogenous mineralocorticoid. It increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration-dependent manner. 11-Dehydrocorticosterone decreases the sodium/creatine ratio and increases the potassium/creatine ratio in rat urine in a dose-dependent manner in a model of 11β-hydroxysteroid dehydrogenase inhibition induced by carbenoxolone Chronic administration 11-dehydrocorticosterone increases plasma glucocorticoids levels, body weight gain, and adiposity, as well as induces insulin resistance in mice.

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