Chitosan (MW 30000)|9012-76-4|(Deacetylated chitin (MW 30000); Poly(D-glucosamine) (MW 30000))-陌孚医药/Medlife

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Chitosan (MW 30000) (Synonyms: Deacetylated chitin (MW 30000); Poly(D-glucosamine) (MW 30000))

目录号: PL14619 纯度: N/A

CAS No. :9012-76-4

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中文名称	Chitosan (MW 30000)
中文别名	甲壳素;2-氨基-β-1,4-葡聚糖;胺聚糖;甲壳胺;聚D-葡糖胺;β-1,4-聚-葡萄糖胺;壳糖葡糖胺;壳聚糖;羧化壳聚糖;(1,4)-2-乙酰胺-2-脱氧-β-D-聚葡萄糖;氨基寡糖素;低聚壳多糖;低聚壳二十四糖平均DP24;低聚壳聚糖;低聚壳六十糖平均DP60;低聚壳六糖平均DP6;低聚壳十二糖平均DP12;低聚壳四十糖平均DP40;低聚壳糖混合物;几丁聚糖;聚氨基葡糖;壳寡糖分子量20000;壳聚寡糖;壳聚糖 (酸溶) 分子量50000;壳聚糖 BR;壳聚糖（水溶）;壳聚糖, 平均分子量 100,000 - 300,000;脱乙酰甲壳质;壳聚糖低粘度<200 mPa.s;壳聚糖高粘度>400 mPa.s;壳聚糖中粘度200-400 mPa.s;壳聚糖10;壳聚糖100;壳聚糖分子量20万;壳聚糖分子量30万食品级;壳聚糖絮凝剂;壳聚糖盐酸盐;食品级壳聚糖;水溶性壳聚糖;水溶性羧化壳聚糖;羧化壳聚糖 BR,水溶性;脱乙酰壳多糖;脱乙酰壳多糖600;脱乙酰壳多糖800;盐酸化壳聚糖 EP标准品;盐酸壳聚糖标准品;2-氨基-beta-1,4-葡聚糖;2-羟丙基三甲基氯化铵壳聚糖;季铵盐壳聚糖水溶性;聚氨基葡萄糖;壳寡糖;可溶性甲壳素;脱乙酰几丁质;絮凝剂;壳聚糖季铵盐;聚(D-葡萄糖胺);几丁聚糖 (200-600mPa·s, 20℃下0.5%于0.5%乙酸溶液中);几丁聚糖 (5-20mPa·s, 20℃下0.5%于0.5%乙酸溶液中);可溶性甲壳质 (5-20mPa·s, 20℃下0.5%于0.5%乙酸溶液中);甲壳胺 (5-20mPa·s, 20℃下0.5%于0.5%乙酸溶液中);脱乙酰几丁质 (5-20mPa·s, 20℃下0.5%于0.5%乙酸溶液中);脱乙酰甲壳质 (5-20mPa·s, 20℃下0.5%于0.5%乙酸溶液中);脱乙酰几丁质 (MW 150000);聚氨基葡糖 (MW 150000);脱乙酰甲壳素 (MW 150000);脱乙酰壳多糖 (MW 150000);几丁聚糖 (MW 150000);甲壳素 (MW 150000);壳聚糖 (MW 150000)
英文名称	Chitosan (MW 30000)
英文别名	Chitosan;POLY(BETA-(1,4)-2-AMINO-2-DEOXY-D-GLUCOSE);POLY(BETA-(1,4)-D-GLUCOSAMINE);POLY(D-GLUCOSAMINE);POLY-(1,4-BETA-D-GLUCOPYRANOSAMINE);4]-BETA-D-GLUCOSAMINE;BETA-(1,4)-2-AMINO-2-DEOXY-D-GLUCOSE;DEACETYLATED CHITIN;CHITOSAN(RG);Carboxylated chitosan;Chitosan, Molecular weight: 600,000-800,000;Poly-D-glucosamine;Chitosan Oligosaccharide;Quaternary chitosan;2-Amino-2-deoxy-(1→4)-β-D-glucopyranan;Poly-(1,4-β-D-glucopyranosamine);Poliglusam;Deacetylchitin;Chicol;Flonac C;Flonac N;Sea Cure Plus;Kytex M;Kytex H;Kimitsu Chitosan L;Sea Cure F;Kimitsu Chitosan H;Kimitsu Chitosan M;Kimitsu Chitosan F;Chitopearl 3510;Kimitsu Chitosan F 2;Chitopearl BC 3000;Chitopearl BCW 3507;Chitopearl BCW 3500;Chitopearl BCW 3000;Chitopearl BCW 2500;Chitopearl BCW 3505;CTA 4;Poliglusam [USAN:INN];Dac 70;EPA Pesticide Chemical Code 128930;YEA;Celox;Chitosan, molecular we;Chitosan (MW 150000);Deacetylated chitin (MW 30000);Poly(D-glucosamine) (MW 30000);Deacetylated chitin (MW 150000);Poly(D-glucosamine) (MW 150000);Poly(beta-(1,4)-2-amino-2-deoxy-D-glucose);Poly(beta-(1,4)-D-glucosamine);Chitosan (MW 30000)
Cas No.	9012-76-4
分子式	C₅₆H₁₀₃N₉O₃₉
分子量	1526.45
包装储存	Powder -20°C 3 years；4°C 2 years

产品详情	Chitosan (MW 30000) (Deacetylated chitin (MW 30000)) 是衍生自几丁质的聚阳离子线性多糖，分子量为 30000。Chitosan 因其无毒，低致敏性，生物相容性和可生物降解性而被广泛使用。Chitosan 还具有抗肿瘤，抗细菌，抗真菌和抗氧化活性。
生物活性	Chitosan (MW 30000) (Deacetylated chitin (MW 30000)) is a polycationic linear polysaccharide derived from chitin with the molecular weight of 30000. Chitosan is an versatile biomaterial because of its non-toxicity, low allergenicity, biocompatibility and biodegradability. Chitosan also has antitumor, antibacterial, antifungal, and antioxidant activities.
性状	Solid
体外研究(In Vitro)	Chitosan (2 mg/mL; 48 hours; SKMEL28 and RPMI7951 cells) treatment presents a reduced growth potential. Chitosan (2 mg/mL; 48 hours; RPMI7951 cells) treatment shows potent pro-apoptotic effects against RPMI7951 through the mitochondrial pathway. Chitosan (2 mg/mL; 48 hours; RPMI7951 cells) treatment induces an up regulation of pro-apoptotic molecules such as Bax and a down regulation of anti-apoptotic proteins like Bcl-2 and Bcl-XL. Low-molecular-weight chitosan can penetrate bacterial cell walls, bind with DNA and inhibit DNA transcription and mRNA synthesis, while high-molecular-weight Chitosan can bind to the negatively charged components on the bacterial cell wall. It forms an impermeable layer around the cell, changes cell permeability and blocks transport into the cell. Chitosan also can be used in water treatment, wound-healing materials, pharmaceutical exci
体内研究(In Vivo)	In chemical-induced colonic precancerous lesions in ICR mice, in the 2 weeks preventive experiments, mice fed with a diet containing high molecular weight Chitosan (HMWC) had significant fewer aberrant crypt foci formation than those fed with control diet. As the treatment extended to 6 weeks, both low molecular weight Chitosan (LMWC)- and HMWC-fed mice contained less aberrant crypt foci when compared to control. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Powder -20°C 3 years；4°C 2 years
参考文献	[1]. Laure Gibot, et al. Anticancer properties of chitosan on human melanoma are cell line dependent. Int J Biol Macromol. 2015 Jan;72:370-9. [2]. Randy Chi Fai Cheung, et al. Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications. Mar Drugs. 2015 Aug 14;13(8):5156-86. [3]. Shyr-Yi Lin, et al. C

溶解度数据	In Vitro: 0.1 M HCL : 5.26 mg/mL (10.49 mM; ultrasonic and adjust pH to 1 with HCl)H₂O : 1.1 mg/mL (2.19 mM; Need ultrasonic)配制储备液

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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