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Ioxilan

目录号: PL14012 纯度: ≥98%

Ioxilan 是一种低渗，非离子和三碘化的诊断造影剂。Ioxilan 还是 X 射线造影剂，用于排泄性尿路造影和头部和身体的造影剂增强计算机断层扫描 (CECT) 成像。血管内注射使造影剂流动路径中的血管变得不透明，从而可以对人体内部结构进行射线照相可视化，直到发生明显的血液稀释为止。

CAS No. :107793-72-6

商品编号	规格	价格	会员价
PL14012-5mg	5mg	¥1768.00	请登录
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PL14012-50mg	50mg	询价	询价
PL14012-100mg	100mg	询价	询价
PL14012-10mM*1mLinDMSO	10mM*1mLinDMSO	¥1944.00	请登录

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中文名称	Ioxilan
中文别名	碘昔兰;5-[乙酰基(2,3-二羟丙基)氨基]-N-(2,3-二羟丙基)-N'-(2-羟乙基)-2,4,6-三碘-1,3-苯二甲酰胺;2-甲氧基-4-氨基-5-硫氰基苯甲酸甲酯;碘昔兰 USP标准品
英文名称	Ioxilan
英文别名	Ioxilan;IOXILAN (400 MG);1,3-Benzenedicarboxamide,5-[acetyl(2,3-dihydroxypropyl)amino]-N1-(2,3-dihydroxypropyl)-N3-(2-h...;5-[acetyl(2,3-dihydroxypropyl)amino]-3-N-(2,3-dihydroxypropyl)-1-N-(2-hydroxyethyl)-2,4,6-triiodobenzene-1,3-dicarboxamide;5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodo-N-(2,3-dihydroxypropyl)-N'-(2-hydroxyethyl)isophthalamide;Imagenil;Ioxitol;Oxilan;5-[Acetyl(2,3-dihydroxypropyl)amino]-N-(2,3-dihydroxypropyl)-N′-(2-hydroxyethyl)-2,4,6-triiodo-1,3-benzenedicarboxamide;Oxilan 300;5-[Acetyl(2,3-dihydroxypropyl)aMino]-N1-(2,3-dihydroxypropyl)-N3-(2-hydroxyethyl)-2,4,6-triiodo-1,3-benzenedicarboxaMide;1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N-(2,3-dihydroxypropyl)-N'-(2-hydroxyethyl)-2,4,6-triiodo-
Cas No.	107793-72-6
分子式	C₁₈H₂₄N₃O₈I₃
分子量	791.11
包装储存	Powder -20°C 3 years；4°C 2 years
详情描述	Ioxilan 是一种低渗，非离子和三碘化的诊断造影剂。Ioxilan 还是 X 射线造影剂，用于排泄性尿路造影和头部和身体的造影剂增强计算机断层扫描 (CECT) 成像。血管内注射使造影剂流动路径中的血管变得不透明，从而可以对人体内部结构进行射线照相可视化，直到发生明显的血液稀释为止。

产品详情	Ioxilan 是一种低渗，非离子和三碘化的诊断造影剂。Ioxilan 还是 X 射线造影剂，用于排泄性尿路造影和头部和身体的造影剂增强计算机断层扫描 (CECT) 成像。血管内注射使造影剂流动路径中的血管变得不透明，从而可以对人体内部结构进行射线照相可视化，直到发生明显的血液稀释为止。
生物活性	Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs.
性状	Solid
体外研究(In Vitro)	As a low-osmolar nonionic monomer, Ioxilan increases the safety and tolerance of X-ray contrast agents. The development of Ioxilan is based on the introduction of a double methylene as a hydrophobic region and masking it with a hydrophilic hydroxyl group could lower the osmolality without adversely affecting the biological tolerance. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	Rapid intravenous injection of water-soluble X-ray contrast agents (Ioxilan) can be performed with dynamic computed tomography to improve the detectability of liver lesions. When injected intravenously, water-soluble, intravenous X-ray contrast agents are largely distributed in the extracellular fluid space and excreted unchanged by the kidneys. Contrast enhancement of a region of interest depends on the route of administration, delivery of the agent to the area by blood flow, and the final iodine concentration in the region. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Powder -20°C 3 years；4°C 2 years
参考文献	[1]. Cheng KT. Ioxilan carbonate particles. National Center for Biotechnology Information (US); 2004-2013. 2007 Sep 1. [2]. Chow SL, et al. Effect of iodixanol and ioxilan on QT interval and renal function in patients with systolic heart failure. Int J Cardiol. 2012 Jan 12;154(1):17-21. [3]. Nonionic Contrast Agent

溶解度数据	In Vitro: DMSO : ≥ 250 mg/mL (316.01 mM)配制储备液

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[1]. Cheng KT. Ioxilan carbonate particles. National Center for Biotechnology Information (US); 2004-2013. 2007 Sep 1.
[2]. Chow SL, et al. Effect of iodixanol and ioxilan on QT interval and renal function in patients with systolic heart failure. Int J Cardiol. 2012 Jan 12;154(1):17-21.
[3]. Nonionic Contrast Agent

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

Ioxilan

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