Gadopentetic acid|80529-93-7|(钆喷酸; Gd-DTPA; gadolinium complex)-陌孚医药/Medlife

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Gadopentetic acid (Synonyms: 钆喷酸; Gd-DTPA; gadolinium complex)

目录号: PL13107 纯度: ≥99.0%

CAS No. :80529-93-7

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中文名称	Gadopentetic acid
中文别名	钆喷酸
英文名称	Gadopentetic acid
英文别名	Gadopentetic acid;Gadolinate(2-), [N,N-bis[2-[bis(carboxymethyl)amino]ethyl]glycinato(5-)]-, dihydrogen;Glycine, N,N-bis[2-[bis(carboxymethyl)amino]ethyl]-, gadolinium complex;(Diethylenetriaminepentaacetato)gadolinium;Diethylenetriaminepentaacetic acid gadolinium(III) dihydrogen salt hydrate;GADOLINIUM(III) DIETHYLENETRIAMINEPENTAACETIC ACID, hydrate;GADOPENTETATE;Acide gadopentetique;Acido gadopentetico;Acidum gadopenteticum;gadolinium 1,1,4,7,7-diethylenetriaminepentaacetate;gadolinium diethylenetriaminepentaacetic acid;gadoliniumdtpa;Gadopentetic;Gd acid spray;Gd(diethylenetriaminepentaacetic acid(-3H));Gd-DTPA;Dihydrogen[3,6,9-tris(carboxylatomethyl)-3,6,9- triazaundecanedioato-κ3N3,N6,N9-gadolinate](2-);Gadolinium(II) diethylenetriaminepentaacetic acid
Cas No.	80529-93-7
分子式	C₁₄H₁₈GdN₃O₁₀^.₂H
分子量	547.57
包装储存	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

产品详情	Gadopentetic acid (Gd-DTPA) 是一种顺磁性造影剂。Gadopentetic acid 在动态对比增强 MRI (DCE-MRI) 研究中，通常经静脉注射实施。Gadopentetic acid 还可用于肾源性系统性纤维化（NSF）的研究。
生物活性	Gadopentetic acid (Gd-DTPA) is a paramagnetic contrast agent. Gadopentetic acid commonly implemented by a bolus intravenous injection in Dynamic contrast-enhanced MRI (DCE-MRI) studies. Gadopentetic acid also can be used for the research of nephrogenic systemic fibrosis (NSF).
性状	Solid
体内研究(In Vivo)	Gadopentetic acid (Gd-DTPA) (tail vein injection; 2 and 5mmol/kg; single) shows systematic metabolic responses involving changes in lipid metabolism, glucose metabolism, TCA cycle, amino acid metabolism and gut microbiota functions in rats. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献	[1]. Wan C, et al. Gd-DTPA-induced dynamic metabonomic changes in rat biofluids. Magn Reson Imaging. 2017 Dec;44:15-25. [2]. Taheri S, et al. Analysis of pharmacokinetics of Gd-DTPA for dynamic contrast-enhanced magnetic resonance imaging. Magn Reson Imaging. 2016 Sep;34(7):1034-40.

溶解度数据	In Vitro: H₂O : 100 mg/mL (182.63 mM; Need ultrasonic)DMSO : 1 mg/mL (1.83 mM; Need ultrasonic)配制储备液

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2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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