Gastric mucin

目录号: PL11757
Gastric mucin 是一种大的糖蛋白,保护胃肠道免受酸、蛋白酶、致病微生物和机械创伤的影响。
CAS No. :84082-64-4
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中文名称
Gastric mucin
中文别名
胃膜素;胃粘膜素;粘蛋白;粘液素II;粘液素III;胃膜素; 胃粘膜素
英文名称
Gastric mucin
英文别名
Gastric Mucin;Gastron;MUCIN TYPE II;GASTRIC MUCIN POWDER(PORCINE);Mucin;3,7-DICHLORO-8-(DICHLOROMETHYL)QUINOLINE;Quinoline, 3,7-dichloro-8-(dichloromethyl)-;3,7-dichloro-8-dichloromethylquinoline;3,7-Dichloro-8-Dichloro Methyl Quinoline;Gastric mucin
Cas No.
84082-64-4
分子式
C10H5Cl4N
分子量
280.97
包装储存
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
详情描述
Gastric mucin 是一种大的糖蛋白,保护胃肠道免受酸、蛋白酶、致病微生物和机械创伤的影响。
产品详情
Gastric mucin 是一种大的糖蛋白,保护胃肠道免受酸、蛋白酶、致病微生物和机械创伤的影响。
生物活性
Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. In Vitro: Gastric mucin may be integrally involved in the mechanism of gastric mucosal injury caused by Helicobacter pylori leading to gastritis, peptic ulceration, and possibly gastric cancer. Gastric mucins are classified into two types based on their histochemical properties. The first is a surface mucous cell-type mucin, secreted from the surface mucous cells. The second is found in deeper portions of the mucosa and is secreted by gland mucous cells, including mucous neck cells, cardiac gland cells, and pyloric gland cells. The unique O-glycans in gastric mucin appears to function as a natural antibiotic, protecting the host from H. pylori
性状
Solid
体外研究(In Vitro)
Gastric mucin may be integrally involved in the mechanism of gastric mucosal injury caused by Helicobacter pylori leading to gastritis, peptic ulceration, and possibly gastric cancer. Gastric mucins are classified into two types based on their histochemical properties. The first is a surface mucous cell-type mucin, secreted from the surface mucous cells. The second is found in deeper portions of the mucosa and is secreted by gland mucous cells, including mucous neck cells, cardiac gland cells, and pyloric gland cells. The unique O-glycans in gastric mucin appears to function as a natural antibiotic, protecting the host from H. pylori infection. Gastric mucin may provide protection to the surface epithelium gastrointestinal tract by scavenging oxidants produced within the lumen; however, it does so at the expense of its viscoelastic properties. Both native and pronase-tr
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
参考文献
[1]. Toribara NW, et al. Human gastric mucin. Identification of a unique species by expression cloning. J Biol Chem. 1993 Mar 15;268(8):5879-85.
[2]. Kawakubo M, et al. Natural antibiotic function of a human gastric mucin against Helicobacter pyloriinfection. Science. 2004 Aug 13;305(5686):1003-6.
[3]. Grisham MB, e
溶解度数据
In Vitro: DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)H2O : < 0.1 mg/mL (ultrasonic) (insoluble)
搜索质检报告(COA)
[1]. Toribara NW, et al. Human gastric mucin. Identification of a unique species by expression cloning. J Biol Chem. 1993 Mar 15;268(8):5879-85.
[2]. Kawakubo M, et al. Natural antibiotic function of a human gastric mucin against Helicobacter pyloriinfection. Science. 2004 Aug 13;305(5686):1003-6.
[3]. Grisham MB, e

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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