Omzotirome

目录号: PL11705 纯度: ≥99%
Omzotirome (TRC150094) 是一种碘甲状腺原氨酸的功能类似物,可用于高脂血症的研究 (WO2008149379)。
CAS No. :1092551-88-6
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中文名称
Omzotirome
中文别名
3-(4-((7-羟基-6-甲基-2,3-二氢-1H-茚-4-基)甲基)-3,5-二甲基-1H-吡唑-1-基)丙酸
英文名称
Omzotirome
英文别名
3-(4-((7-Hydroxy-6-methyl-2,3-dihydro-1H-inden-4-yl)methyl)-3,5-dimethyl-1H-pyrazol-1-yl)propanoic acid;3-(4-((7-hydroxy-6-methyl-2,3-dihydro-1H-inden-4-yl)methyl)-3,5-dimethyl-1Hpyrazol-1-yl)propanoic acid;3-[4-[(7-hydroxy-6-methyl-2,3-dihydro-1H-inden-4-yl)methyl]-3,5-dimethylpyrazol-1-yl]propanoic acid;4-[(2,3-dihydro-7-hydroxy-6-methyl-1H-inden-4-yl)methyl]-3,5-dimethyl-1H-Pyrazole-1-propanoic acid;Omzotirome
Cas No.
1092551-88-6
分子式
C19H24N2O3
分子量
328.41
包装储存
4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
详情描述
Omzotirome (TRC150094) 是一种碘甲状腺原氨酸的功能类似物,可用于高脂血症的研究 (WO2008149379)。
产品详情
Omzotirome (TRC150094) 是一种碘甲状腺原氨酸的功能类似物,可用于高脂血症的研究 (WO2008149379)。
生物活性
Omzotirome (TRC150094), a functional analog of iodothyronines, can be used for the research of hyperlipidaemia (WO2008149379).
性状
Solid
体内研究(In Vivo)
Omzotirome (0.750 mg/ 100 g; i.p.) with high-fat diet rats have significantly less visceral adipose tissue (vs. HFD rats) and exhibit altered metabolism in two major tissues that are very active metabolically and exhibit increased energy expenditure and body weight (BW) gain comparable to that of standard chow-fed rats.
Omzotirome, a functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet (HFD). has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
ClinicalTrial
参考文献
[1]. WO2008149379
[2]. Cioffi F, et al. TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet. FASEB J. 2010;24(9):3451-3461.
溶解度数据
In Vitro: DMSO : 100 mg/mL (304.50 mM; Need ultrasonic)配制储备液
搜索质检报告(COA)
[1]. WO2008149379
[2]. Cioffi F, et al. TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet. FASEB J. 2010;24(9):3451-3461.

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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