Hypromellose

目录号: PL08579
Hypromellose是用于形成溶胀溶解性基质的亲水性非离子纤维素醚。
CAS No. :9004-65-3
商品编号 规格 价格 会员价 是否有货 数量
PL08579-500mg 500mg ¥642.00 请登录
PL08579-1g 1g ¥803.00 请登录
PL08579-5g 5g ¥286.00 请登录
PL08579-10g 10g ¥390.00 请登录
Medlife所售产品仅用于科学研究(非临床研究),非药品不可食用,不可用于人体或动物的临床诊断和治疗,我们不为个人提供产品及服务。产品COA等资料,可至下方“质量控制”中下载。
*注意事项:下单时请联系销售核实产品价格及货期,避免后续产生不便,感谢支持!
中文名称
Hypromellose
中文别名
羟丙基甲基纤维素;羟基丙酸甲基纤维素;羟甲基丙基纤维素;羟丙甲纤维素;羟基丙基甲基纤维素;羥丙基甲基纖維素;低取代-羟丙纤维素 L-HPC;(羟丙基)甲基纤维素;PVC级羟丙基甲基纤维素;低取代羟丙纤维素;高取代羟丙基纤维素;建筑级羟丙基甲基纤维素;羟丙基-甲基纤维素;羟丙基甲基纤维素 瓷砖级;羟丙基甲基纤维素 15万;羟丙基甲基纤维素 HPMC;羟丙基甲基纤维素 USP标准品;羟丙基甲基纤维素 立釜式 hpmc;羟丙基甲基纤维素 腻子用保水率高;羟丙基甲基纤维素 乳胶漆用 hpmc;羟丙基甲基纤维素 砂浆用高纯度;羟丙基甲基纤维素 造纸用;羟丙基甲基纤维素 自流平砂浆用;羟丙基甲基纤维素(HPMC);羟丙基甲基纤维素(低取代);羟丙基甲基纤维素(高取代);羟丙基甲基纤维素 II型,粘度:400mPa.s;羟丙基甲基纤维素 I型,粘度:30mPa.s;羟丙基甲基纤维素 I型,粘度:400mPa.s;羟丙基甲基纤维素20000;羟丙基甲基纤维素醚;食品级羟丙基甲基纤维素;涂料 hpmc 羟丙基甲基纤维素;纤维素;医药级羟丙基甲基纤维素;II型,粘度:100mPa.s;干粉砂浆专用羟丙基甲基纤维素;羟丙基甲基纤维素 II型,粘度:100mPa.s;羟丙基甲基纤维素 II型,粘度:15000mPa.s;羟丙基甲基纤维素 II型,粘度:4000mPa.s;羟丙基甲基纤维素 I型,粘度:100mPa.s;羟丙基甲基纤维素 I型,粘度:20000mPa.s;羟丙基甲基纤维素 I型,粘度:4000mPa.s;羟丙基甲基纤维素 II型,粘度:100000mPa.s;羟丙基甲基纤维素 低黏度,150-400mpas;羟丙基甲基纤维素 高黏度,30000mpas;羟丙基甲基纤维素 特高粘度,100000mpas;羟丙基甲基纤维素 中黏度,4000-6500mpas;羟丙基甲基纤维素,Hydroxypropylmethylcellulose,II型,粘度:400mPa.s;羟丙基甲基纤维素,Hydroxypropylmethylcellulose,I型,粘度:30mPa.s;羟丙基甲基纤维素,Hydroxypropylmethylcellulose,I型,粘度:400mPa.s;羟丙甲纤维素,纤维素羟丙基甲基醚;纤维素羟丙基甲基醚;羟丙基甲基纤维素 2910;合肥羟丙基甲基纤维素、芜湖羟丙基甲基纤维素;羟丙甲纤维素9004-65-3供应商;羟丙甲纤维素厂家销售;高粘度羟丙基甲基纤维素;速溶羟丙基甲基纤维素;羟丙甲基纤维素K4M
英文名称
Hypromellose
英文别名
Hydroxypropyl methyl cellulose;MODIFIED CELLULOSE;PROPYLENE GLYCOL ETHER OF METHYLCELLULOSE;HPMC;HYPOMELLOSE 2208;HYPOMELLOSE 2906;HYPOMELLOSE 2910;HYPROMELLOSE;HYPROMELLOSE, 2208;Hydroxypropylmethylcellulose (HPMC);Hydroxyl Propyl Methyl Cellulose;(Hydroxypropyl)methyl cellulose;Celacol HPM 5000;E464;MHPC;Hydroxy Propyl Methyl Cellulose;High viscosity hypromellose;Instant hydroxypropyl methyl cellulose;Polyvinyl Alcohol
Cas No.
9004-65-3
分子式
C36H70O19.C20H38O11
分子量
1261.44
包装储存
Powder -20°C 3 years;4°C 2 years
详情描述
Hypromellose是用于形成溶胀溶解性基质的亲水性非离子纤维素醚。
产品详情
Hypromellose是用于形成溶胀溶解性基质的亲水性非离子纤维素醚。
生物活性
Hypromellose is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.
性状
Solid
体外研究(In Vitro)
Hypromellose provides the release of a drug in a controlled manner, effectively increasing the duration of release of a drug to prolong its therapeutic effect. Hypromellose (hydroxypropylmethylcellulose) has been used in sustained-release pharmaceutical products for many years. When used in matrix tablets, these polymers hydrate on contact with water to produce a viscous gel barrier within and surrounding the tablet. The properties of hypromellose that affect the rate of drug release include the rate of diffusion of water into the dry polymer, the rate of hypromellose hydration and gel formation, the viscosity of the hydrated hypromellose and rate of hypromellose gel erosion. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
Punctal occlusion using hypromellose 2% is a low-cost and safe additional treatment for dry eye. Fluorescein and rose bengal staining tests show that there was a significant reduction in signs after occlusion using hypromellose. Hypromellose is effective in improving the blood glucose metabolism and suppressing oxidative stress in mice fed with a high fat diet. The antihyperglycemic and antioxidative effects of hypromellose could be partly attributed to the regulation of hepatic glucose-regulating enzyme activities and activation of the hepatic and erythrocyte antioxidant enzymes. Hypromellose may be useful as biomaterials in the development of functional food or as therapeutic agents against high fat-induced hyperglycemia and oxidative stress. has not independently confirmed the accuracy of these methods. They are for
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
ClinicalTrial
参考文献
[1]. Li CL, et al. The use of hypromellose in oral drug delivery. J Pharm Pharmacol. 2005 May;57(5):533-46.
[2]. Braund R, et al. Hypromellose films for the delivery of growth factors for wound healing.
[3]. Capita L, et al. Prospective evaluation of hypromellose 2% for punctal occlusion in patients with dry eye. Co
溶解度数据
In Vitro: DMSO : 25 mg/mL (Need ultrasonic)H2O : 10 mg/mL (Need ultrasonic)In Vivo:
搜索质检报告(COA)
[1]. Li CL, et al. The use of hypromellose in oral drug delivery. J Pharm Pharmacol. 2005 May;57(5):533-46.
[2]. Braund R, et al. Hypromellose films for the delivery of growth factors for wound healing.
[3]. Capita L, et al. Prospective evaluation of hypromellose 2% for punctal occlusion in patients with dry eye. Co

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2