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Argireline

目录号: PL08554 纯度: ≥99.0%

Argireline (Acetyl hexapeptide-3) 是一种无毒，可渗透皮肤的抗皱肽。Argireline 可显着抑制神经肌肉接头处依赖 Ca²⁺ 的神经递质释放。Argireline 具有抗皱和抗衰老的作用。

CAS No. :616204-22-9

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PL08554-500mg	500mg	询价	询价

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中文名称	Argireline
中文别名	阿基瑞林;醋酸阿基瑞林;六胜肽;六胜肽阿基瑞林 Acetyl Hexapeptide-8;六胜肽,阿基瑞林;美容肽-阿基瑞林 Argireline Acetate (Acetyl Hexapeptide-3);美容肽-阿基瑞林 ArgirelineAcetate (AcetylHexapeptide-3);乙酰基六肽-8;阿基瑞林,乙酰基六肽-3,乙酰基六肽-8,Acetyl Hexapeptide-3;阿基瑞林美容肽,化妆品肽;抗皱胜肽;祛皱复合肽;乙酰六胜肽-3;乙酰六肽;乙酰基六肽-8/阿基瑞林/六胜肽/乙酰六胜肽-3;乙酰六肽-8
英文名称	Argireline
英文别名	Argireline;N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamide;Acetyl hexapeptide;Acetyl hexapeptide-3;AC-GLU-GLU-MET-GLN-ARG-ARG-NH2;Argireline Acetate;Argreline Acetate;Mechano Growth Factor (MGF);Acetyl Hexapeptide-8;Ac-Glu-Glu-Met-Glu-Arg-Arg-NH2;Argirelin Acetate(Acetyl Hexapeptide-3);Argireline Acetate anti-aging cosMetic peptide;Acetyl Hexapeptide-8/Argireline/Acetyl Hexapeptide-3;C34H60N14O12S;V1479;204A229
Cas No.	616204-22-9
分子式	C₃₄H₆₀N₁₄O₁₂S
分子量	888.99
包装储存	Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year
详情描述	Argireline (Acetyl hexapeptide-3) 是一种无毒，可渗透皮肤的抗皱肽。Argireline 可显着抑制神经肌肉接头处依赖 Ca²⁺ 的神经递质释放。Argireline 具有抗皱和抗衰老的作用。

产品详情

生物活性

Argireline (Acetyl hexapeptide-3) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline significantly inhibits Ca dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity.

性状

Solid

体外研究(In Vitro)

The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Cellular proliferation is not effected in Argireline low concentration. has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究(In Vivo)

Argireline is applied to the aged mice twice daily for 6 weeks. There is an improvement in the histological structure of skin tissue in the aged mice; the amount of type I collagen fibers increased, while that of type III collagen fibers decreased. Argireline could improve the histological structure of skin tissue and rejuvenate the aging skin. has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year

ClinicalTrial

SequenceShortening

Ac-EEMQRR-NH2

参考文献

[1]. Blanes-Mira C, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002 Oct;24(5):303-10.
[2]. Grosicki M, et al. The study of cellular cytotoxicity of argireline - an anti-aging peptide. Acta Biochim Pol. 2014;61(1):29-32.
[3]. Wang Y, et al. The anti-wrinkle efficacy of Ar

溶解度数据	In Vitro: H₂O : 100 mg/mL (112.49 mM; Need ultrasonic)配制储备液

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产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

Argireline

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