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Mas7

目录号: PL08541 纯度: ≥96%

Mas7 (Mastoparan 7) 是 mastoparan 的结构类似物，是异源三聚体 Gi 蛋白及其下游效应物的活化剂。

CAS No. :145854-59-7

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中文名称	Mas7
中文别名	胡蜂蜂毒肽 7
英文名称	Mas7
英文别名	L-Leucinamide,L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-;Mastoparan-7;ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2;L-Leucinamide,L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L...;L-Leucinamide,L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alan;Mas 7;Mastoparan7;INLKALAALAKALL-NH2;Mastoparan from Polistes jadwagae;H-ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2;Mas7
Cas No.	145854-59-7
分子式	C₆₇H₁₂₄N₁₈O₁₅
分子量	1421.81
包装储存	Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year
详情描述	Mas7 (Mastoparan 7) 是 mastoparan 的结构类似物，是异源三聚体 Gi 蛋白及其下游效应物的活化剂。

产品详情	Mas7 (Mastoparan 7) 是 mastoparan 的结构类似物，是异源三聚体 Gi 蛋白及其下游效应物的活化剂。
生物活性	Mas7 (Mastoparan 7), a structural analogue of mastoparan, is an activator of heterotrimeric Gi proteins and its downstream effectors.
性状	Solid
体外研究(In Vitro)	Mas7 (Mastoparan 7) produces several biological effects in different cell types. The effect of Mas7 on endogenous mono-ADP-ribosyltransferase activity is in the micromolar range with a maximal activation of 205% over the basal. In pertussis treated plasma membranes, it is found that the effect of Mas7 on endogenous mono-ADP-ribosyltransferase is partially blocked, which suggests the involvement of G-proteins, such as Gi or G0. Mas7 is a basic tetradecapeptide isolated from isp venom, which activates guanine nucleotide-binding regulatory proteins (G-proteins) and stimulates apoptosis. In smooth muscle cells, Mas7 leads to an increase in the perfusion pressure. Vascular contraction is induced by Mas7. The vasoconstriction triggered by mas-7 exhibited a slower increase compared to that simulated by phenylephrine or vasopressin. Exposure of hippocampal neurons to a low d
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year
SequenceShortening	INLKALAALAKALL-NH2
Sequence	Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Ala-Leu-Leu-NH2
参考文献	[1]. Bavec A, et al. Novel features of amphiphilic peptide Mas7 in signalling via heterotrimeric G-proteins. J Pept Sci. 2004 Nov;10(11):691-9. [2]. Grze?k G, et al. Direct regulation of vascular smooth muscle contraction by mastoparan-7. Biomed Rep. 2014 Jan;2(1):34-38. [3]. Ramírez VT, et al. The Gαo Activator Mas

溶解度数据	In Vitro: H₂O : 1 mg/mL (0.70 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 50°C)

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[1]. Bavec A, et al. Novel features of amphiphilic peptide Mas7 in signalling via heterotrimeric G-proteins. J Pept Sci. 2004 Nov;10(11):691-9.
[2]. Grze?k G, et al. Direct regulation of vascular smooth muscle contraction by mastoparan-7. Biomed Rep. 2014 Jan;2(1):34-38.
[3]. Ramírez VT, et al. The Gαo Activator Mas

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

Mas7

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