Eslicarbazepine|104746-04-5|(艾司利卡西平; BIA 2-194)-陌孚医药/Medlife

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Eslicarbazepine (Synonyms: 艾司利卡西平; BIA 2-194)

目录号: PL08422 纯度: ≥99%

CAS No. :104746-04-5

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PL08422-50mg	50mg	¥4661.00	请登录
PL08422-100mg	100mg	¥7232.00	请登录
PL08422-200mg	200mg	询价	询价
PL08422-500mg	500mg	询价	询价
PL08422-10mM*1mLinDMSO	10mM*1mLinDMSO	¥1060.00	请登录

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中文名称	Eslicarbazepine
中文别名	(S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺;艾司利卡西平
英文名称	Eslicarbazepine
英文别名	(S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide;(S)-10-Monohydroxy-10,11-dihydro Carbamazepine (Eslicarbazepine);S-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN;(S)-10-Monohydroxy-1;(S)-10-Monohydroxy-10,11-dihydro Carbamazepine (Eslicarbazepine);(S)-10-Monohydroxy-dihydro-carbamazepine (Eslicarbazepine);5H-Dibenz[b,f]azepine-5-carboxamide,10,11-dihydro-10-hydroxy-, (10S)-;S-Licarbazepine;(+)-Licarbazepine;(10S)-10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide;(S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide;(S)-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide;5-hydroxy-4a,5-dihydro-4H-dibenzo[b,f]azepine-10-carboxamide;eslicarbazepine;MHD;S5VXA428R4;(S)-10-Monohydroxydihydrocarbamazepine;(S)-Licarbazepine;(10S)-;(10S)-10,11-DIHYDRO-10-HYDROXY CARBAMAZEPINE;(S)-10-Monohydroxy-dihydro-carbamazepine (Eslicarbazepine);(S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepin-5-carboxamide;5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-, (10S)-;Eslicarbazepine
Cas No.	104746-04-5
分子式	C₁₅H₁₄N₂O₂
分子量	254.28
包装储存	Powder -20°C 3 years；4°C 2 years

产品详情

Eslicarbazepine (BIA 2-194) 是一种口服抗惊厥试剂，可用于局部癫痫的辅助研究。

生物活性

Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.

性状

Solid

体内研究(In Vivo)

Eslicarbazepine is an anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. Eslicarbazepine acetate is a prodrug for eslicarbazepine (S-licarbazepine), which is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel. has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder -20°C 3 years；4°C 2 years

ClinicalTrial

参考文献

[1]. Finelli E, et al. Patch testing in a case of eslicarbazepine and carbamazepine induced cutaneous reaction. Eur Ann Allergy Clin Immunol. 2018 Sep;50(5):229-231.
[2]. Sibhghatulla Shaikh, et al. Aptiom (Eslicarbazepine Acetate) as a Dual Inhibitor of β-Secretase and Voltage-Gated Sodium Channel: Advancement in Alzheimers Disease-Epilepsy Linkage via an Enzoinformatics Study. CNS & Neurological Disorders Drug Targets V

溶解度数据	In Vitro: DMSO : 250 mg/mL (983.17 mM; Need ultrasonic)配制储备液

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Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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