Please store the product under the recommended conditions in the Certificate of Analysis.
详情描述
Alemtuzumab (Campath-IH) 是一种抗 CD52 的人源化单克隆抗体,CD52 是一种糖蛋白,在大多数淋巴细胞表面表达,在较小程度上也表达于髓细胞类型。阿仑单抗选择性靶向 CD52 抗原,诱导淋巴细胞深度耗竭,然后恢复具有调节表型的 T 细胞和 B 细胞。
产品详情
Alemtuzumab (Campath-IH) 是一种抗 CD52 的人源化单克隆抗体,CD52 是一种糖蛋白,在大多数淋巴细胞表面表达,在较小程度上也表达于髓细胞类型。阿仑单抗选择性靶向 CD52 抗原,诱导淋巴细胞深度耗竭,然后恢复具有调节表型的 T 细胞和 B 细胞。
生物活性
Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52, a glycoprotein expressed on the surface of most lymphoid, and to a lesser extent, myeloid cell types. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes.
性状
Liquid
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
ClinicalTrial
参考文献
[1]. Kashani N, et al. Immune Regulatory Cell Bias Following Alemtuzumab Treatment in Relapsing-Remitting Multiple Sclerosis. Front Immunol. 2021;12:706278. Published 2021 Oct 28.
[1]. Kashani N, et al. Immune Regulatory Cell Bias Following Alemtuzumab Treatment in Relapsing-Remitting Multiple Sclerosis. Front Immunol. 2021;12:706278. Published 2021 Oct 28.