Triheptanoin (Propane-1,2,3-triyl triheptanoate) 是一种合成的中链甘油三酯 (MCT)，由甘油主链上的三个奇数链 7-碳（庚酸）脂肪酸组成。可用于遗传代谢紊乱的研究。

Triheptanoin (Propane-1,2,3-triyl triheptanoate) is a synthetic medium-chain triglyceride (MCT) consisting of three odd-chain 7-carbon (heptanoate) fatty acids on a glycerol backbone. Triheptanoin can be used for the research of inherited metabolic disorders.

Liquid

In long-chain fatty acid oxidation disorders (LC-FAOD), Triheptanoin is used as an anaplerotic compound, acting as a source of calories and fatty acids to bypass the LC-FAOD enzyme deficiencies.
Triheptanoin can be used for the research of ataxia-telangiectasia (A-T).
Triheptanoin functions as an anaplerotic agent replenishing tricarboxylic acid (TCA) cycle intermediates by metabolism to heptanoate (C7) and subsequently acetyl-CoA and propionyl-CoA that feed into the TCA cycle to supply energy.
Triheptanoin mitigates brain ATP depletion and mitochondrial dysfunction, including respiration and redox balance in a mouse model of Alzheimers disease, supporting the energy failure hypothesis for that disorder.
Triheptanoin (Mice were treated with Triheptanoin (35E%) for 10 days prior to pilocarpine injection to induce status epilepticus) preserved mitochondrial func

Room temperature in continental US; may vary elsewhere.

4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

[1]. Matt Shirley. Triheptanoin: First Approval. Drugs. 2020 Oct;80(15):1595-1600.
[2]. A J Yeo, et al. An anaplerotic approach to correct the mitochondrial dysfunction in ataxia-telangiectasia (A-T). Mol Metab. 2021 Dec;54:101354.
[3]. Kah Ni Tan, et al. Triheptanoin protects against status epilepticus-induced hip

In Vitro: DMSO : 100 mg/mL (233.31 mM; Need ultrasonic)配制储备液