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2-Deoxy-D-glucose 6-phosphate disodium

目录号: PL08320 纯度: ≥98.0%

2-Deoxy-D-glucose 6-phosphate disodium 是 2-Deoxy-D-glucose 的衍生物，在哺乳动物细胞中由己糖激酶作用于 2-DG 产生。2-Deoxy-D-glucose 6-phosphate disodium 是葡萄糖代谢的竞争性抑制剂，通过对己糖激酶的作用抑制糖酵解。

CAS No. :33068-19-8

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中文名称	2-Deoxy-D-glucose 6-phosphate disodium
中文别名	2-脱氧-d-葡萄糖 6-磷酸钠;2-脱氧-D-葡萄糖-6-磷酸钠盐
英文名称	2-Deoxy-D-glucose 6-phosphate disodium
英文别名	D-arabino-Hexose,2-deoxy-, 6-(dihydrogen phosphate), disodium salt (8CI);2-DEOXY-D-GLUCOSE-6-PHOSPHATE SODIUM SALT;sodium,(2,3,4-trihydroxy-6-oxohexyl) dihydrogen phosphate;2-Deoxy-D-glucose 6-phosphate sodium salt;2-Deoxy-D-glucose 6-phosphate disodium
Cas No.	33068-19-8
分子式	C₆H₁₃O₈P^.₂Na
分子量	266.12
包装储存	-20°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
详情描述	2-Deoxy-D-glucose 6-phosphate disodium 是 2-Deoxy-D-glucose 的衍生物，在哺乳动物细胞中由己糖激酶作用于 2-DG 产生。2-Deoxy-D-glucose 6-phosphate disodium 是葡萄糖代谢的竞争性抑制剂，通过对己糖激酶的作用抑制糖酵解。

产品详情	2-Deoxy-D-glucose 6-phosphate disodium 是 2-Deoxy-D-glucose 的衍生物，在哺乳动物细胞中由己糖激酶作用于 2-DG 产生。2-Deoxy-D-glucose 6-phosphate disodium 是葡萄糖代谢的竞争性抑制剂，通过对己糖激酶的作用抑制糖酵解。
生物活性	2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.
性状	Oil
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-20°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30. [2]. B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234.

溶解度数据	In Vitro: H₂O : 250 mg/mL (867.75 mM; Need ultrasonic)配制储备液

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[1]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.
[2]. B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234.

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

2-Deoxy-D-glucose 6-phosphate disodium

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