购物车0
产品总数：61489
| 中文名称 |
Prolactin Releasing Peptide (1-31), human
|
|---|---|
| 中文别名 |
催乳素PROLACTIN RELEASING PEPTIDE (1-31)
|
| 英文名称 |
Prolactin Releasing Peptide (1-31), human
|
| 英文别名 |
Prolactin-Releasing Peptide (1-31) (human);H-SER-ARG-THR-HIS-ARG-HIS-SER-MET-GLU-ILE-ARG-THR-PRO-ASP-ILE-ASN-PRO-ALA-TRP-TYR-ALA-SER-ARG-GLY-ILE-ARG-PRO-VAL-GLY-A...;Prolactin-Releasing Peptide (1-31) (human), PrRP31 (human), Preprolactin (23-53) (human);(3S)-4-[[(2S,3S)-1-[[(2S)-4-Amino-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[;Prolactin Releasing Peptide (1-31), human;L-Phenylalaninamide, L-threonyl-L-prolyl-L-alpha-aspartyl-L-isoleucyl-L-asparaginyl-L-prolyl-L-alanyl-L-tryptophyl-L-tyrosyl-L-alanyl-L-seryl-L-arginylglycyl-L-isoleucyl-L-arginyl-L-prolyl-L-valylglycyl-L-arginyl-;Prolactin-Releasing Peptide (12-31) (human);H-Ser-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-Arg-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2;PrRP31 (huMan), Preprolactin (23-53) (huMan);Human PrRP-31
|
| Cas No. |
215510-22-8
|
| 分子式 |
C104H158N32O26
|
| 分子量 |
2272.57
|
| 包装储存 |
Sealed storage, away from moisture and light, under nitrogenPowder -80°C 2 years；-20°C 1 ye
|
| 产品详情 |
Prolactin Releasing Peptide (1-31), human 是一种高亲和力的 GPR10 配体，可引起催乳素的释放。Prolactin Releaving Peptide (1-31) 与人和大鼠的 GPR10 结合，Ki 值分别为 1.03 nM 和 0.33 nM。Prolactin Releasing Peptide (1-31) 可用于下丘脑-垂体轴的研究。
|
|---|---|
| 生物活性 |
Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin. Prolactin Releasing Peptide (1-31) binds to GPR10 for human and rats with K i values of 1.03 nM and 0.33 nM, respectively. Prolactin Releasing Peptide (1-31) can be used for the research of the hypothalamo-pituitary axis.
|
| 性状 |
Solid
|
| 体外研究(In Vitro) |
Prolactin Releasing Peptide (1-31) binds to GPR10 for human and rats with Ki values of 1.03 nM and 0.33 nM, respectively. has not independently confirmed the accuracy of these methods. They are for reference only.
|
| 体内研究(In Vivo) |
Prolactin Releasing Peptide (1-31) (human) (ICV, 5 nM) increases plasma FSH, total plasma testosterone and significantly increased the release of LHRH from hypothalamic explants in vitro.
Prolactin Releasing Peptide (1-31) (human) (ICV, 100 nM) increases the hypothalanic peptides involved in the control of pituitary hormone release, vasoactive intestinal peptide (VIP) and galanin but had no effect on orexin A secretion. has not independently confirmed the accuracy of these methods. They are for reference only.
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
Sealed storage, away from moisture and light, under nitrogenPowder -80°C 2 years；-20°C 1 ye
|
| SequenceShortening |
SRTHRHSMEIRTPDINPAWYASRGIRPVGRF-NH2
|
| Sequence |
Ser-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-Arg-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2
|
| Solvent&Solubility |
In Vitro:
H2O Peptide Solubility and Storage Guidelines:1. Calculate the length of the peptide.2. Calculate the overall charge of the entire peptide according to the following table: |
| 参考文献 |
[1]. Langmead CJ, et al. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G[2]. L J Seal, et al. Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. Endocrinology. 2000 May;141(5):1909-12.
|
1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。
2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。
Copyright © 2025 陌孚医药 All rights reserved 未经授权禁止拷贝本站所有资料，如有违反，将追究法律责任。
沪ICP备2023012080号 | 
沪公网安备31011402010657号
扫码关注公众号
产品使用指南
