DSPE-PEG(2000)-Amine (Synonyms: DSPE-PEG-NH2, MW 2000 ammonium)
目录号: PL06720 纯度: ≥98.0%
CAS No. :474922-26-4
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中文名称
DSPE-PEG(2000)-Amine
中文别名
DSPE-PEG-NH2
英文名称
DSPE-PEG(2000)-Amine
英文别名
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (ammonium salt);DSPE-PEG(2000)-Amine;DSPE-PEG-Amine (MW 2000) (ammonium)
Cas No.
474922-26-4
分子式
(C2H4O)NC44H87N2O10P.H3N
包装储存
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
产品详情
DSPE-PEG(2000)-Amine 是一种磷脂聚乙二醇的胺衍生物,用于合成固体脂质和热敏脂质体纳米颗粒,以递送抗癌剂。
生物活性
DSPE-PEG(2000)-Amine, an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.
性状
Solid
体外研究(In Vitro)
DSPE-PEG(2000)-Amine is coated on the surface of the fluorescein diacetate (FDA) nanocrystals to provide a interface for the antibody coupling. The FDA[DSPE-PEG(2000)Amine]-modified biolabels have a highly stable colloidal suspension with minimized nonspecific interactions. The adsorbed DSPE-PEG(2000)Amine layer causes the FDA nanocrystals to disperse in water and prevents their aggregation, hence conferring colloidal stability. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献
[1]. Feilong Sun, et al. A Mixed Micelle Formulation for Oral Delivery of Vitamin K. Pharm Res. 2016 Sep;33(9):2168-79.
[2]. Brian R Sloat, et al. In Vitro and in Vivo Anti-Tumor Activities of a Gemcitabine Derivative Carried by Nanoparticles. Int J Pharm. 2011 May 16;409(1-2):278-88.
[3]. Cangel Pui-yee Chan, et al
溶解度数据
In Vitro: Ethanol : 16.67 mg/mL (Need ultrasonic)DMSO : 7.14 mg/mL (ultrasonic and warming and heat to 60°C)In Vivo:
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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