DSPE-PEG(2000)-Amine, an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.
性状
Solid
体外研究(In Vitro)
DSPE-PEG(2000)-Amine is coated on the surface of the fluorescein diacetate (FDA) nanocrystals to provide a interface for the antibody coupling. The FDA[DSPE-PEG(2000)Amine]-modified biolabels have a highly stable colloidal suspension with minimized nonspecific interactions. The adsorbed DSPE-PEG(2000)Amine layer causes the FDA nanocrystals to disperse in water and prevents their aggregation, hence conferring colloidal stability. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献
[1]. Feilong Sun, et al. A Mixed Micelle Formulation for Oral Delivery of Vitamin K. Pharm Res. 2016 Sep;33(9):2168-79.[2]. Brian R Sloat, et al. In Vitro and in Vivo Anti-Tumor Activities of a Gemcitabine Derivative Carried by Nanoparticles. Int J Pharm. 2011 May 16;409(1-2):278-88.[3]. Cangel Pui-yee Chan, et al
溶解度数据
In Vitro: Ethanol : 16.67 mg/mL (Need ultrasonic)DMSO : 7.14 mg/mL (ultrasonic and warming and heat to 60°C)In Vivo: