CCP peptide TFA

目录号: PL05937 纯度: ≥96%
CCP peptide TFA 是一种合成的环状瓜氨酸化肽 (CCP),用作血清学检测抗 CCP 抗体的底物。CCP peptide TFA 可作为自身抗体的靶标,对类风湿关节炎 (RA) 具有很高的特异性。
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PL05937-1mg 1mg ¥3777.00 请登录
PL05937-5mg 5mg ¥8840.00 请登录
PL05937-10mg 10mg ¥15028.00 请登录
PL05937-50mg 50mg 询价 询价
PL05937-100mg 100mg 询价 询价
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中文名称
CCP peptide TFA
英文名称
CCP peptide TFA
包装储存
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
详情描述
CCP peptide TFA 是一种合成的环状瓜氨酸化肽 (CCP),用作血清学检测抗 CCP 抗体的底物。CCP peptide TFA 可作为自身抗体的靶标,对类风湿关节炎 (RA) 具有很高的特异性。
产品详情
CCP peptide TFA 是一种合成的环状瓜氨酸化肽 (CCP),用作血清学检测抗 CCP 抗体的底物。CCP peptide TFA 可作为自身抗体的靶标,对类风湿关节炎 (RA) 具有很高的特异性。
生物活性
CCP peptide TFA is a synthetic cyclic citrullinated peptide (CCP) and used as the substrate for detecting anti-CCP antibodies serologically. CCP peptide TFA functions as a target for autoantibodies with a very high specificity for rheumatoid arthritis (RA).
性状
Solid
体内研究(In Vivo)
CCP peptide is used as a new antigenic substrate in anti-CCP ELISA to detect anti-citrullinated protein antibodies (ACPAs). The anti-CCP ELISA is extremely specific (98%), with a reasonable sensitivity (68%). The anti-CCP ELISA is very useful for diagnostic and therapeutic strategies in rheumatoid arthritis (RA). has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
SequenceShortening
HQCHQEST-{Cit}-GRSRGRCGRSGS(Disulfide bridge: Cys3-Cys16)
Sequence
His-Gln-Cys-His-Gln-Glu-Ser-Thr-{Cit}-Gly-Arg-Ser-Arg-Gly-Arg-Cys-Gly-Arg-Ser-Gly-Ser (Disulfide bridge: Cys3-Cys16)
参考文献
[1]. Puszczewicz M, et al. Role of anti-citrullinated protein antibodies in diagnosis and prognosis of rheumatoid arthritis. Arch Med Sci. 2011 Apr;7(2):189-94.
[2]. S?derlin MK, et al. Antibodies against cyclic citrullinated peptide (CCP) and levels of cartilage oligomeric matrix protein (COMP) in very early arthritis: relation to diagnosis and disease activity. Scand J Rheumatol. 2004;33(3):185-8.
溶解度数据
In Vitro: H2O : 5 mg/mL (2.04 mM; Need ultrasonic)配制储备液
搜索质检报告(COA)
[1]. Puszczewicz M, et al. Role of anti-citrullinated protein antibodies in diagnosis and prognosis of rheumatoid arthritis. Arch Med Sci. 2011 Apr;7(2):189-94.
[2]. S?derlin MK, et al. Antibodies against cyclic citrullinated peptide (CCP) and levels of cartilage oligomeric matrix protein (COMP) in very early arthritis: relation to diagnosis and disease activity. Scand J Rheumatol. 2004;33(3):185-8.

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2