Serotonin-d4|58264-95-2|(5-Hydroxytryptamine-d-陌孚医药/Medlife

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Serotonin-d4 (Synonyms: 5-Hydroxytryptamine-d

目录号: PL05519 纯度: ≥99%

CAS No. :58264-95-2

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中文名称	Serotonin-d4
中文别名	[ 2H4 ] -5 - 羟色胺标准品;血清素-D4;羟色胺-D4
英文名称	Serotonin-d4
英文别名	[2H4]-5-Hydroxytryptamine;Serotonin-d4;3-(2-AMinoethyl-d4)-1H-indol-5-ol Hydrochloride;5-HydroxytryptaMine-d4;Hippophaine-d4;5-Hydroxytryptamine hydrochloride salt;Serotonin D4 HydrochlorideQ: What is Serotonin D4 Hydrochloride Q: What is the CAS Number of Serotonin D4 Hydrochloride Q: What is the storage condition of Serotonin D4 Hydrochloride Q: What are the applications of Serotonin D4 Hydrochloride
Cas No.	58264-95-2
分子式	C₁₀H₁₂N₂O
分子量	180.24
包装储存	Please store the product under the recommended conditions in the Certificate of Analysis.

产品详情	Serotonin-d₄ 是 Serotonin 氘代物。Serotonin 是 CNS 中的单胺神经递质和内源性 5-HT 受体激动剂。Serotonin 也是儿茶酚 O-甲基转移酶 (COMT) 的抑制剂，其 K_i 值为 44 μM。
生物活性	Serotonin-d 4 is deuterium labeled Serotonin. Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
体外研究(In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Tsao D, et al. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Mol Pain. 2012 Apr 13;8:25.

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