您当前的位置：

L-Leucyl-L-Leucine methyl ester hydrobromide

(Synonyms: LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide)

目录号: PL03081 纯度: ≥99%

L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide 是人单核细胞或多形核白细胞产生的 L-亮氨酸甲酯的二肽缩合产物，可选择性消除具有细胞毒性潜能的淋巴细胞。L-Leucyl-L-Leucine methyl ester hydrobromide 也可以诱导溶酶体途径应激。

CAS No. :16689-14-8

商品编号	规格	价格	会员价
PL03081-5mg	5mg	¥803.00	请登录
PL03081-10mg	10mg	¥1285.00	请登录
PL03081-25mg	25mg	¥2410.00	请登录
PL03081-50mg	50mg	¥3616.00	请登录
PL03081-100mg	100mg	¥5304.00	请登录
PL03081-200mg	200mg	询价	询价
PL03081-500mg	500mg	询价	询价

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

*注意事项:下单时请联系销售核实产品价格及货期，避免后续产生不便，感谢支持!

加入购物车在线咨询收藏产品大包装询价

中文名称	L-Leucyl-L-Leucine methyl ester hydrobromide
中文别名	Leu-leu甲酯氢溴酸;L-亮氨酰-L-亮氨酸甲酯盐酸盐
英文名称	L-Leucyl-L-Leucine methyl ester hydrobromide
英文别名	(S)-Methyl 2-((S)-2-amino-4-methylpentanamido)-4-methylpentanoate hydrobromide;H-LEU-LEU-OME · HBR;Leu-Leu methyl ester hydrobromide;L-Leucine, L-leucyl-,methyl ester, monohydrobromide (9CI);H-Leu-Leu-OMe·HCl;LLME,HBr Leu-Leu-Ome,HBr;methyl 2-[(2-amino-4-methylpentanoyl)amino]-4-methylpentanoate,hydrobromide;LLME · HBr;H-Leu-Leu-OMe;Leu-Leu-Ome, HBr;H-LEU-LEU-OME HBR;L-Leucyl-L-Leucine methyl ester hydrobromide
Cas No.	16689-14-8
分子式	C₁₃H₂₆N₂O₃^.HBr
分子量	339.27
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
详情描述	L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide 是人单核细胞或多形核白细胞产生的 L-亮氨酸甲酯的二肽缩合产物，可选择性消除具有细胞毒性潜能的淋巴细胞。L-Leucyl-L-Leucine methyl ester hydrobromide 也可以诱导溶酶体途径应激。

产品详情	L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide 是人单核细胞或多形核白细胞产生的 L-亮氨酸甲酯的二肽缩合产物，可选择性消除具有细胞毒性潜能的淋巴细胞。L-Leucyl-L-Leucine methyl ester hydrobromide 也可以诱导溶酶体途径应激。
生物活性	L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress.
性状	Solid
体外研究(In Vitro)	L-Leucyl-L-Leucine methyl ester (1 mM; 0.5-2 h) enhances LRRK2-mediated Rab10 and Rab12 phosphorylation in MEFs and A549 cells. L-Leucyl-L-Leucine methyl ester (10-250 μM; 15 min) is converted to a CCI3COOH-insoluble product by CD4 lymphocytes. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Thiele DL, et, al. The immunosuppressive activity of L-leucyl-L-leucine methyl ester: selective ablation of cytotoxic lymphocytes and monocytes. J Immunol. 1986 Feb 1;136(3):1038-48. [2]. Thiele DL, et, al. Mechanism of L-leucyl-L-leucine methyl ester-mediated killing of cytotoxic lymphocytes: dependence on a lysosomal thiol protease, dipeptidyl peptidase I, that is enriched in these cells. Proc Natl Acad Sci U S A. 1990 Jan;87(1):83-7.

溶解度数据	In Vitro: DMSO : 250 mg/mL (736.88 mM; Need ultrasonic)H₂O : 100 mg/mL (294.75 mM; Need ultrasonic)配制储备液

搜索质检报告(COA)

产品使用指南

Data Sheet

[1]. Thiele DL, et, al. The immunosuppressive activity of L-leucyl-L-leucine methyl ester: selective ablation of cytotoxic lymphocytes and monocytes. J Immunol. 1986 Feb 1;136(3):1038-48.
[2]. Thiele DL, et, al. Mechanism of L-leucyl-L-leucine methyl ester-mediated killing of cytotoxic lymphocytes: dependence on a lysosomal thiol protease, dipeptidyl peptidase I, that is enriched in these cells. Proc Natl Acad Sci U S A. 1990 Jan;87(1):83-7.

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

L-Leucyl-L-Leucine methyl ester hydrobromide

相关产品

The molarity calculator equation

The dilution calculator equation