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DHBP dibromide

(Synonyms: Diheptylviologen dibromide)

目录号: PL01196 纯度: ≥99%

DHBP dibromide是钙离子释放的抑制剂和肌肉松弛剂。

CAS No. :6159-05-3

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PL01196-10mM*1mLinDMSO	10mM*1mLinDMSO	¥884.00	请登录

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中文名称	DHBP dibromide
中文别名	1,1'-二庚基-4,4'-二溴化联吡啶鎓;1,1'-二庚基-4,4'-二溴化联吡啶鎓[用于电致变色材料];1,1 -二庚基-4,4 -二吡啶鎓二溴化物 [用于电致变色材料];1,1'-二庚基-4,4'-二吡啶鎓二溴化物 [用于电致变色材料];二溴化-1,1`-二庚基-4,4`-联吡啶鎓;二溴化-1,1ˊ-二庚基-4,4ˊ-联吡啶鎓;二溴化-1,1-二庚基-4,4-联吡啶;二溴化-1,1'-二庚基-4,4'-联吡啶鎓
英文名称	DHBP dibromide
英文别名	1,1'-Diheptyl-[4,4'-bipyridine]-1,1'-diium bromide;1,1'-Diheptyl-4,4'-bipyridinium Dibromide [for Electrochromic Material];1,1'-Diheptyl-4,4'-bipyridinium dibromide;4,4'-Bipyridinium,1,1'-diheptyl-, bromide (1:2);DHBP dibromide;1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBROMIDE;heptyl viologen dibromide;heptylviologen bromide;N,N'-diheptyl-4,4bipyridinium dibromide;N,N'-diheptyl-4,4'-dipyridinium dibromide;DHBP (dibromide);4,4'-Bipyridinium, 1,1'-diheptyl-, dibromide;4,4'-Bipyridinium, 1,1'-diheptyl-, bromide (1:2);1-heptyl-4-(1-heptylpyridin-1-ium-4-yl)pyridin-1-ium dibromide;C24H38Br2N2;VRXAJMCFEOESJO-UHFFFAOYSA-L;HMS3411P05;HMS3266J14;HMS3675P;Diheptylviologen dibromide
Cas No.	6159-05-3
分子式	C₂₄H₃₈Br₂N₂
分子量	514.38
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
详情描述	DHBP dibromide是钙离子释放的抑制剂和肌肉松弛剂。

产品详情	DHBP dibromide是钙离子释放的抑制剂和肌肉松弛剂。
生物活性	DHBP dibromide is an inhibitor for calcium release and a muscle relaxant.
性状	Solid
体外研究(In Vitro)	DHBP inhibits the calcium release induced by 2 mM caffeine and 2 μg/mL polylysine with an IC50 value of 5 μg/mL and 4 μg/mL, respectively. DHBP inhibits [H]-ryanodine binding in a dose-dependent manner with an IC50 of 2.5 μg/mL and 90-100% inhibition at 20-30 μg/mL. Calcium uptake by SR is inhibited in the presence of caffeine and this inhibition is antagonized by concomitant addition of DHBP. Muscle twitches elicited by direct electrical muscle stimulation and contractions induced by either 10 mM caffeine or 1 fLM ryanodine are blocked by pretreatment with DHBP. DHBP blocks the calcium release from SR by direct interaction with the calcium release channel, also known as the ryanodine receptor. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Kang JJ, et al. Effects of bipyridylium compounds on calcium release from triadic vesicles isolated from rabbit skeletal muscle. Br J Pharmacol. 1994 Aug;112(4):1216-22.

溶解度数据	In Vitro: H₂O : 100 mg/mL (194.41 mM; Need ultrasonic)DMSO : ≥ 30 mg/mL (58.32 mM)

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[1]. Kang JJ, et al. Effects of bipyridylium compounds on calcium release from triadic vesicles isolated from rabbit skeletal muscle. Br J Pharmacol. 1994 Aug;112(4):1216-22.

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

DHBP dibromide

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