Oleoylcarnitine|38677-66-6|酮、醛、酸|PC65859-1mg|Medlife,上海现货

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Oleoylcarnitine

Oleoylcarnitine 是一种通过抑制脂肪酸 β-氧化而积累的代谢物，可通过 STAT3 的激活而增强肝癌的发生。Oleoylcarnitine 是一种通过抑制脂肪酸 β-氧化而积累的代谢物，可通过 STAT3 的激活而增强肝癌的发生。

目录号: PC65859 纯度: ≥98.0%

CAS No. :38677-66-6

商品编号	规格	价格	会员价	是否有货	数量
PC65859-1mg	1mg	询价	询价

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中文名称	Oleoylcarnitine
英文名称	Oleoylcarnitine
英文别名	Oleoyl-L-carnitine;Oleoylcarnitine;Oleoyllevocarnitine;(R)-oleoylcarnitine;IQ19DDF3A0;oleoyl L-carnitine;Oleoylcarnitine, (-)-;O-oleoyl-L-carnitine;(9Z)-octadecenoyl-L-carnitine;(R)-[(9Z)-octadecenoyl]carnitine;BDBM50537046;C18:1(.DELTA.9-cis) Carnitine;O-(9Z)-octadecenoyl-(R)-carnitine;Oleoyl-L-carnitine, analytical standard;1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-(((9Z)-1-oxo-9-octadecenyl)oxy)-, inner salt, (2R)-;1-Propanaminium, 3-car
Cas No.	38677-66-6
分子式	C₂₅H₄₇NO₄
分子量	425.65
包装储存	Powder； -20°C； 3 years；In solvent； -80°C； 6 months；

生物活性	Oleoylcarnitine, the metabolite which accumulates through suppression of fatty acid β-oxidation, can enhance hepatocarcinogenesis via STAT3 activation.
性状	Solid
IC50 & Target[1][2]	Human Endogenous Metabolite

体外研究(In Vitro)

Oleoylcarnitine (AC18:1) (5, 25, 50 μM; 24, 48 hours) concentration significantly increases in the Dih10 cells with stable CPT2 knock down.
Oleoylcarnitine (5 μM, 24 hours) contributes directly to hepatocarcinogenesis by conferring stem cell properties to cancer cells through STAT3 activation.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Viability Assay

体内研究(In Vivo)

Oleoylcarnitine (AC18:1) accumulates markedly in obesity-driven HCC tissues of mice.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model:MUP-uPA and PIK3CA Tg mice.

运输条件

Room temperature or refrigerated transport.

储存方式

Powder； -20°C； 3 years；In solvent； -80°C； 6 months；

结构分类

Ketones, Aldehydes, Acids