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Glucosamine hydrochloride

(Synonyms: 盐酸氨基葡萄糖; D-(+)-Glucosamine hydrochloride; Chitosamine hydrochloride)

目录号: PC63841 纯度: 10mM*1mLinDMSO

Glucosamine hydrochloride (D-Glucosamine hydrochloride) 是一种氨基糖, 是糖基化蛋白和脂质生化合成的突出前体, 用作膳食补充剂。Glucosamine hydrochloride也是软骨基质和滑液中糖胺聚糖的天然成分，当外用时，对骨关节炎软骨和软骨细胞具有药理作用。Glucosamine hydrochloride (D-Glucosamine hydrochloride) 是一种氨基糖, 是糖基化蛋白和脂质生化合成的突出前体, 用作膳食补充剂。Glucosamine hydrochloride也是软骨基质和滑液中糖胺聚糖的天然成分，当外用时，对骨关节炎软骨和软骨细胞具有药理作用。

CAS No. :66-84-2

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PC63841-1mg	1mg	询价	询价
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中文名称	Glucosamine hydrochloride
中文别名	氨基葡萄糖盐酸盐;2-氨基-2-脱氧-D-氨基葡萄糖盐酸盐;葡糖胺盐酸盐;葡萄糖胺盐酸盐;氨基葡(萄)糖盐酸;盐酸-Α-D-氨基葡糖;盐酸氨基葡萄糖;盐酸甲壳质;氨基酸葡萄糖盐酸盐;葡萄胺糖;2-氨基葡萄糖;Α-D-葡糖胺盐酸盐;D（+）-氨基葡萄糖盐酸盐;D-(+)-葡萄糖胺盐酸盐;D-(+)-Glucosamine Hydrochloride； D-(+)-葡萄糖胺盐酸盐;DC级氨基葡萄糖硫酸钠盐(载体HPMC);D-Glucosamine ；D-氨基葡萄糖;D-氨基葡萄糖;D-氨基葡萄糖盐酸盐;D-氨基葡萄糖盐酸盐；D-Glucosamine hydrochloride;D-氨基葡萄糖盐酸盐,BR;D-盐酸氨基葡萄糖;氨基葡萄糖硫酸盐;氨基葡萄糖为系统适应性 EP标准品;氨基葡萄糖盐;氨基葡萄糖盐酸盐 EP标准品;氨基葡萄糖盐酸盐[纯虾蟹壳];氨糖;氨糖（D-氨基葡萄糖盐酸盐）;葡萄糖胺盐酸盐 USP标准品;盐酸氨基葡萄糖标准品;盐酸氨基葡萄糖（标准品）;盐酸氨基葡萄糖；D-氨基葡萄糖盐酸盐;盐酸氨基葡萄糖；Glucosamine Hydrochloride;盐酸葡萄糖胺;盐酸葡萄糖胺, D-(+)-(P);D(+)-葡萄糖胺,盐酸盐;D-氨基葡萄糖盐酸盐；2-氨基-2-脱氧-D-氨基葡萄糖盐酸盐；2-氨基-2-脱氧-D-葡萄糖盐酸盐；壳糖胺盐酸盐;D-葡糖胺盐酸盐;氨基葡糖 HCL;氨糖盐酸;葡糖胺 HCL;2-氨基-2-脱氧-D-葡萄糖盐酸盐;壳糖胺盐酸盐;α-D-氨基葡糖盐酸盐;D-(+)-氨基葡萄糖盐酸盐;D-(+)-盐酸葡糖胺;D-(+)-葡糖胺盐酸盐;氨基葡萄糖盐酸盐，医药级,纯度:>99%
英文名称	Glucosamine hydrochloride
英文别名	D-Glucosamine hydrochloride;2-AMINO-2-DEOXY-D-GLUCOPYRANOSE HYDROCHLORIDE;2-AMINO-2-DEOXY-D-GLUCOSE HCL;2-AMINO-2-DEOXY-D-GLUCOSE HYDROCHLORIDE;2-AMINO-D-GLUCOSE HYDROCHLORIDE;2-DESOXY-2-AMINO-D-GLUCOSE HYDROCHLORIDE;CHITOSAMINE;CHITOSAMINE HCL;CHITOSAMINE HYDROCHLORIDE;D-GLCN HCL;D-(+)-GLUCOSAMINE HCL;D-GLUCOSAMINE HCL;D(+)-GLUCOSAMINE HYDROCHLORIDE;GLUCOSAMINE HCL;GLUCOSAMINE HCL, D-(+)-;GLUCOSAMINE HYDROCHLORIDE;2-Amido-2-deoxy-D-glucosaminehydrochloride;2-amino-2-deoxy-d-glucoshydrochloride;cosamin;D-Glucose,2-amino-2-deoxy-,hydrochloride;D-(+)-Glucosamine Hydrochloride;(2R,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride;D(+)-Glucosamin-hydrochlorid;Glucopyranose, 2-amino-2-deoxy-, hydrochloride, D-;GLUCOSAMINE HCL, D-(+)-(P) PrintBack;refine D-Glucosamine hydrochloride;2-amino-D-2-deoxy-glucose, hydrochloride;2-Glucosamine;D-glucoasamine hydrochloride;D-GlucosaMine HC1;glucosamine-hydrochloride;(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochloride;DSSTox_CID_17236;DSSTox_RID_79312;DSSTox_GSID_37236;SMR000718786;GlcN.HCl;glucosamine HCl salt;Glucosamine-HCl salt;PubChem18037;D-Aminoglucose hydrochloride;MLS001335940;MLS001335939;MLS001332571;MLS002695991;2-Amino-2-deoxy-glucose HCl;d-glucosamine hydroch
Cas No.	66-84-2
分子式	C₆H₁₄ClNO₅
分子量	215.63
包装储存	4°C, sealed storage and away from moisture；*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage and away from moisture)；

生物活性

Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine hydrochloride also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.

性状

Solid

IC50 & Target[1][2]

Human Endogenous Metabolite
Microbial Metabolite

体外研究(In Vitro)

Glucosamine hydrochloride (D-Glucosamine hydrochloride) exhibits dose-dependent DPPH antioxidant activity.
Glucosamine hydrochloride treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins.
Glucosamine hydrochloride significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature or refrigerated transport.

储存方式

4°C, sealed storage and away from moisture；*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage and away from moisture)；

ClinicalTrial

结构分类

Saccharides

来源

crustaceans and other arthropods, fungi

参考文献

[1]. Bruyère O, et al. Efficacy and safety of glucosamine sulfate in the management of osteoarthritis: Evidence from real-life setting trials and surveys. Semin Arthritis Rheum. 2016 Feb;45(4 Suppl):S12-7.
[2]. Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9.

溶解度数据	体外研究: DMSO : 100 mg/mL(463.76 mM;Need ultrasonic) H₂O : 50 mg/mL(231.88 mM;Need ultrasonic) 配制储存液

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Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

Glucosamine hydrochloride

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