(S)-MG132

MG-132蛋白酶体抑制剂;MG132 抑制剂;MG132,蛋白酶体抑制剂;蛋白酶体抑制剂;N-[(苄氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-L-亮氨酰胺

(S)-MG132

L-Leucinamide,N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-;MG-132;(S)-MG132;Benzyl (S)-4-methyl-1-((S)-4-methyl-1-((S)-4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-ylcarbamate;benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate;CALPAIN INHIBITOR IV;MG 132 (MG-132);MG-132-1;N-CBZ-LEU-LEU-LEU-AL;ProteasoMe Inhibitor MG-132;Z-Leu-Leu-Leu-H (Aldehyde);MG132;Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal;Cbz-Leu-Leu-Leu-H;Z-LEU-LEU-LEU-AL;Z-Leu-Leu-Leu-CHO;Z-Leu-Leu-Leu-H;Z-LLL-CHO;Calpain inhibitor IV-2;N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide;Z-LL-CHO;Z-LEU-LEU-ALDEHYDE;MG132/MG-132;MG-132, >=98%;Zlllal;MG 132;Zlll-cho;Z-Leu-leu-leucinal;Carbobenzoxy-leucyl-leucyl-leucinal;Benzyloxycarbonyl-leu-leu-leu-aldehyde;Benzyloxycarbonyl-leucyl-leucyl-leucinal;Lll cpd;Carbobenzoxyl-leucinyl-leucinyl-leucinal-H;Benzyloxycarbonylleucyl-leucyl-leucine aldehyde

133407-82-6

C₂₆H₄₁N₃O₅

475.62

MG-132 (Z-Leu-Leu-Leu-al) 是一种有效的，可逆的蛋白酶体 (proteasome) 抑制剂，IC50 为 100 nM。MG-132 有效阻断 26S 蛋白酶体复合物的蛋白水解活性。MG-132 是一种肽醛，是自噬 (autophagy) 激活剂。MG-132 还诱导凋亡 (apoptosis)。