FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process.
性状
Solid
体外研究(In Vitro)
FeTPPS acts as an effective pro-oxidant towards appreciable substrates 体外研究 in the presence of oxidant. FeTPPS protects cells against oxidative damage induced by H2O2, generated by Glucose (G)-glucose oxidase (GO) system.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay
Cell Line:
Human hepatocellular carcinoma (HepG2)
Concentration:
5, 10, 15, 20, 25?μM
Incubation Time:
Treated 12?h before being exposed to H2O2
Result:
Could protect cells against oxidative damage induced by H2O2.