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Adenosine-5'-diphosphate
体内能量储存,代谢和信号转导的中心成分;嘌呤能受体的激动剂,Adenosine 5'-diphosphate 是核苷二磷酸,是 ATP 酶对 ATP 去磷酸化的产物。
目录号: PC12742 纯度: ≥98%
CAS No. :58-64-0
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中文名称
Adenosine-5'-diphosphate
中文别名
腺苷-5-二磷酸二钠盐;腺苷-5’-二磷酸;(需冷藏);5''-二磷酸腺苷;6-硝基苯并(a)芘;二磷酸腺苷;二磷酸腺苷 ADP;二磷酸腺苷酸;腺苷-5′-二磷酸;腺苷-5'-二磷酸;腺苷-5-二磷酸;腺苷5-二磷酸;5`-二磷酸腺苷.K;5'-二磷酸腺苷;腺苷-5`-二磷酸
英文名称
Adenosine-5'-diphosphate
英文别名
((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate;Adenosine 5'-diphosphate;ADENOSINE 5'-DIPHOSPHATE DISODIUM;Adenosine-5-Diphosphate;ADP;5′-ADP;Adenosine 5′-diphosphate;Adenosine5'-(trihydrogen pyrophosphate) (8CI);Adenosine diphosphate (6CI);5'-ADP;ADP (nucleotide);Adenosine 5'-diphosphoric acid;Adenosine 5'-pyrophosphate;Adenosine 5'-pyrophosphoric acid;Adenosinepyrophosphate;Adenosine, 5'-(trihydrogen diphosphate);a-ADP;adenosine 5'-(trihydrogen diphosphate);Adenosine diphosphate;adenosine pyrophosphate;adenosine-5'-diphosphate;adenosine-diphosphate;5'-Adenylphosphoric acid;Adenosindiphosphorsaeure;Adenosine-5'-diphosphat;Adenosine diphosphoric acid;Ado-5'-P-P;H3adp;61D2G4IYVH;adenosine-5-dipho;Adenosine 5’-diphosphate;Adenosine 5'-(trihydrogen pyrophosphate) (8CI); Adenosine diphosphate (6CI); α-ADP; Adenosine, 5'-(trihydrogen diphosphate); Adenosine pyrophosphate; Adenosine 5'-pyrophosphoric acid; Adenosine 5'-pyrophosphate; Adenosine 5'-diphosphoric acid; Adenosine 5'- diphosphate; ADP (nucleotide); 5'-ADP
Cas No.
58-64-0
分子式
C10H15N5O10P2
分子量
427.20
包装储存

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

生物活性

Adenosine 5-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

性状

Solid

IC50 & Target[1][2]

Human Endogenous Metabolite

 

体外研究(In Vitro)

Adenosine 5-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature or refrigerated transportation.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

ClinicalTrial
结构分类
参考文献
溶解度数据
体外研究: 

H2O : 50 mg/mL (117.04 mM; Need ultrasonic)

配制储备溶液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.3408 mL 11.7041 mL 23.4082 mL
5 mM 0.4682 mL 2.3408 mL 4.6816 mL
10 mM 0.2341 mL 1.1704 mL 2.3408 mL
*

产品不同,其溶解度不同。建议根据产品选择合适的溶剂配制储备溶液;配成溶液后,建议分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,建议在 6 个月内使用,-20°C 储存时,建议在 1 个月内使用。

体内研究:

建议根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都建议先按照 体外研究 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    建议依照次序添加每种溶剂: PBS

    Solubility: 100 mg/mL (234.08 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

*
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

The molarity calculator equation
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The dilution calculator equation
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