Sulfaguanidine-C 6 is the C 6 labeled Sulfaguanidine. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.
性状
Solid
体外研究(In Vitro)
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.[2]. LOWELL A, et, al. THE USE OF SULFAGUANIDINE IN THE TREATMENT OF DYSENTERY CARRIERS. JAMA. 1942 Apr; 118(15):1268-1271.[3]. Mizuno N, et, al. Gastrointestinal absorption of sulfaguanidine in neonatal and adult rat