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| 中文名称 |
Methyl cellulose
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|---|---|
| 中文别名 |
甲基纤维素;纤维素甲醚;甲基纤维素, 黏度 8000 CPS;甲基纤维素, 黏度 4000 CPS;甲基纤微素;甲基纤维素(15MPA.S~100000MPA.S);高粘度甲基纤维素;中粘度甲基纤维素(4000 MPA.S);甲基纤维素 MC 粘度 1700MPA.S;甲基纤维素 USP标准品;甲基纤维素(药用);甲基纤维素,MC-15 CP;甲基纤维素,MC-20 CP;甲基纤维素,MC-400 AR;甲基纤维素,MC-400 CP;甲基纤维素 BR,超高粘度15000Mpa.s;甲基纤维素 BR,低粘度25Mpa.s;甲基纤维素 BR,高粘度3500-5600Mpa.s;甲基纤维素 BR,中粘度350-550Mpa.s;甲基纤维素100;甲基纤维素15;甲基纤维素1500;甲基纤维素25;甲基纤维素400;甲基纤维素4000;甲基纤维素50;甲基纤维素M450;甲基纤维素参照样品;BR,中粘度350-550Mpa.s;甲基纤维素（MC）;甲基纤维素, 黏度 15 cPs;纤维素甲基醚;甲基纤维素 (3,500-5,600mPa·s, 20℃时2%的水溶液);纤维素甲基醚 (3,500-5,600mPa·s, 20℃时2%的水溶液);纤维素甲醚 (3,500-5,600mPa·s, 20℃时2%的水溶液);纤维素甲醚 (13-18mPa·s, 20℃时2%的水溶液);纤维素甲醚 (20-30mPa·s, 20℃时2%的水溶液);纤维素甲醚 (80-120mPa·s, 20℃时2%于水中);纤维素甲醚 (350-550mPa·s, 20℃时2%的水溶液);纤维素甲醚 (1,000-1,800mPa·s, 20℃时2%的水溶液);纤维素甲醚 (7,000-10,000mPa·s, 20℃时2%的水溶液)
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| 英文名称 |
Methyl cellulose
|
| 英文别名 |
Methyl cellulose;MODIFIED CELLULOSE;MODIFIED CELLULOSE, MC;'TYLOSE'(R) MH 300;'TYLOSE'(R) MH 1000;adulsin;Methyl cellulose, viscosity 8000 cPs;Methyl cellulose, viscosity 4000 cPs;Methyl cellulose M20;METHYLCELLULOSE, 4,000 CENTIPOISES;Methyl cellulose, viscosity 15 cPs;Methylcellulose (AS);Methocel® MC;Methyl ether cellulose;Methylcellulose;Methyl cellulose, viscosity 400 cP (2% solution in water);Methyl cellulose, viscosity 15 cP (2% solution in water);Methyl cellulose, viscosity 4000 cP (2% solution in water);FEMA 2696;(5R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-{[(2S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy}oxane;(5R)-2,3,4-Trimethoxy-6-(methoxymethyl)-5-[(2S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane
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| Cas No. |
9004-67-5
|
| 分子式 |
C20H38O11
|
| 分子量 |
454.51
|
| 包装储存 |
Powder -20°C 3 years；4°C 2 years
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| 产品详情 |
Methyl cellulose 是一种非离子纤维素醚，具有独特的热胶凝性质，没有毒性。
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|---|---|
| 生物活性 |
Methylcellulose is a natural polymer which gels on heating. Methylcellulose is not toxic.
|
| 性状 |
Solid
|
| 体内研究(In Vivo) |
Protocal for preparing 0.5% Methylcellulose Solution
Measure 0.5g of dry Methylcellulose and dissolved in 100 ml ddH2O/0.9% Saline (0.9 g NaCl in 100 ml ddH2O) to make a clear solution.
Under the condition of stirring and heating (50-65°C), adding Methylcellulose slowly to ddH2O/0.9% Saline helps to accelerate dissolution.
Note
1.You must ensure that your Methylcellulose solution does not exist solid-liquid separation phenomenon. The solution is in a uniform and transparent state has no particles in it.
2.Completely dissolution of Methylcellulose may requires 4 hours or more longer.
0.5% Methylcellulose solution (0.5% MC) can be used for oral adminstration or intraperitoneal injection. has not independently confirmed the accuracy of these methods. They are for reference only.
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
Powder -20°C 3 years；4°C 2 years
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| ClinicalTrial |
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| 参考文献 |
[1]. Stacey Meeker, et al. Repeated Intraperitoneal Administration of Low-Concentration Methylcellulose Leads to Systemic Histologic Lesions Without Loss of Preclinical Phenotype. J Pharmacol Exp Ther. 2019 Oct;371(1):25-35
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| 溶解度数据 |
In Vitro: H2O : 1 mg/mL (Need ultrasonic)
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|---|
1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。
2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。
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