STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly.
性状
Solid
体外研究(In Vitro)
STING agonist-7 (compound 11) is active in biochemical assays but inactive in cellular reporter assays. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献
[1]. Emily C Cherney, et al. Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization. J Med Chem. 2022 Feb 24;65(4):3518-3538.
溶解度数据
In Vitro: DMSO : 62.5 mg/mL (185.85 mM; Need ultrasonic)配制储备液