STING-IN-2
目录号: PL11523 纯度: ≥98%
CAS No. :346691-38-1
商品编号 规格 价格 会员价 是否有货 数量
PL11523-10mg 10mg ¥803.00 请登录
PL11523-25mg 25mg ¥1607.00 请登录
PL11523-50mg 50mg ¥2571.00 请登录
PL11523-100mg 100mg ¥4018.00 请登录
PL11523-200mg 200mg 询价 询价
PL11523-500mg 500mg 询价 询价
PL11523-10mM*1mLinDMSO 10mM*1mLinDMSO ¥884.00 请登录
Medlife所售产品仅用于科学研究(非临床研究),非药品不可食用,不可用于人体或动物的临床诊断和治疗,我们不为个人提供产品及服务。产品COA等资料,可至下方“质量控制”中下载。
中文名称
STING-IN-2
英文名称
STING-IN-2
英文别名
N-(4-butylphenyl)-5-nitro-2-furamide;STING-IN-2
Cas No.
346691-38-1
分子式
C15H16N2O4
分子量
288.30
包装储存
Powder -20°C 3 years;4°C 2 years
产品详情
STING-IN-2 (C-170) 是一种有效且共价的 STING 抑制剂。STING-IN-2 有效抑制小鼠 STING (mmSTING) 和人类 STING (hsSTING)。STING-IN-2 可用于自身炎症性疾病的研究。
生物活性
STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). STING-IN-2 can be used for autoinflammatory disease research.
性状
Solid
体外研究(In Vitro)
THP-1 cells are pretreated with STING-IN-2 (C-170; 0.5 μM) and stimulated with cGAMP. STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
参考文献
[1]. Simone M Haag, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273.
溶解度数据
In Vitro: DMSO : 125 mg/mL (433.58 mM; Need ultrasonic)配制储备液
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2