Hydroxymetronidazole-d4|1215071-08-1|-陌孚医药/Medlife

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Hydroxymetronidazole-d4

目录号: PL08843

CAS No. :1215071-08-1

商品编号	规格	价格	会员价	是否有货	数量
PL08843-1mg	1mg	询价	询价
PL08843-10mg	10mg	询价	询价

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中文名称	Hydroxymetronidazole-d4
中文别名	2,3,5-三苯甲酰氧基-2-C-甲基-D-核糖酸-1,4-内酯;羟基甲硝唑-d4
英文名称	Hydroxymetronidazole-d4
英文别名	Hydroxy Metronidazole-d4;1,1,2,2-tetradeuterio-2-[2-(hydroxymethyl)-5-nitroimidazol-1-yl]ethanol;Hydroxymetronidazole-d4
Cas No.	1215071-08-1
分子式	C₆H₉N₃O₄
分子量	187.15
包装储存	Please store the product under the recommended conditions in the Certificate of Analysis.

产品详情	Hydroxymetronidazole-d₄ 是 Hydroxymetronidazole 的氘代物。Hydroxymetronidazole (Metronidazole-OH) 是一种 Metronidazole 的代谢产物，属于硝基咪唑类。Hydroxymetronidazole 可用于研究家禽中的某些细菌和原生动物疾病，以及牛痢疾和牛生殖器滴虫病。
生物活性	Hydroxymetronidazole-d 4 is the deuterium labeled Hydroxymetronidazole. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle[1].
体外研究(In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Rodrigo H M M Granja, et al. Determination and confirmation of metronidazole, dimetridazole, ronidazole and their metabolites in bovine muscle by LC-MS/MS. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(6):970-6.

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