Prednisone|53-03-2|(强的松; Dehydrocortisone)-陌孚医药/Medlife

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Prednisone (Synonyms: 强的松; Dehydrocortisone)

目录号: PL05288 纯度: ≥99%

CAS No. :53-03-2

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PL05288-10mM*1mLinDMSO	10mM*1mLinDMSO	¥884.00	请登录

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中文名称	Prednisone
中文别名	泼尼松;泼尼松片（溶出检测用标准片）;17Α,21-二羟基-1,4-孕甾二烯-3,11,20-三酮;去氢肾上腺皮质激素;脱氢可的松;强的松;去氢可的松;170,21-二羟基-Δ1,4-孕甾二烯-3,11,20-三酮,17Α,21-DIHYDROXY-1,4-PREGNADIENE-3,11,20-TRIONE;泼尼松,PREDNISONE;去氢皮质素;泼尼松原粉;甲醇中泼尼松溶液标准物质;强的松标准品;泼尼松片;泼尼松校正片;去氢可的
英文名称	Prednisone
英文别名	prednisone;1,4-PREGNADIEN-17,21-DIOL-3,11,20-TRIONE;1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE;1,4-PREGNADIENE-17ALPHA,21-DIOL-3,11,20-TRIONE;17ALPHA,21-DIHYDROXY-1,4-PREGNADIENE-3,11,20-TRIONE;17ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE;1-CORTISONE;1-DEHYDROCORTISONE;(8S,9S,10R,13S,14S,17R)-17-HYDROXY-17-(2-HYDROXY-ACETYL)-10,13-DIMETHYL-7,8,9,10,12,13,14,15,16,17-DECAHYDRO-6H-CYCLOPENTA[A]PHENANTHRENE-3,11-DIONE;DEHYDROCORTISONE;DELTA1-CORTISONE;PREDNISON;PREDNISONUM;1,2-Dehydrocortisone;1,4-pregnadiene-16-alpha,21-diol-3,11,20-trione;11,20-trione,17,21-dihydroxy-pregna-4-diene-3;11,20-trione,17,21-hydroxy-pregna-4-diene-3;Ancortone;Bicortone;Colisone;17,21-Dihydroxypregna-1,4-diene-3,11,20-trione;Prednisone Solution;prednisone base;Cortidelt;-Cortisone;Dacortin;Decortancyl;Decortisyl;Dekortin;Delta-Cortelan;Deltacortisone;Deltacortone;Delta-E;Deltasone;Deltison;Deltisone;Deltra;Di-Adreson;Encorton;Encortone;Enkorton;Hostacortin;Metacortandracin;Meticorten;NSC 10023;Paracort;Prednizon;Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-;Rectodelt;Supercortil;Ultrac;1,4-Pregnadiene-17a,21-diol-3,11,20-trione;Decortin;Orasone;Ultracorten;Sterapred;Prednilonga;Cortan;Liquid Pred;Zenadrid;Ultracortene;Pronison;Diadreson;Panafcort;Lisacort;Servisone;Prednidib;Winpred;Cotone;Wojtab;Panasol;Adas;.delta.1-Dehydrocortisone;Cartancyl;BRD-K85883481-001-08-3;delta-1-Cortisone;Parmenison;Metrevet (Veterinary);MEGxm0_000443;delta cortelan;PREDNISONE [INN];Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone;Nisona;Prednicorm;SK-Prednisone;D0IL7L;1,21-diol-3,11,20-trione;AI3-52939;prednisone anhydrous;Prednovister;BRD-K85883481-001-25-7;MLS002207083;PREDNISONE [WHO-DD];HMS3259I09;AS-11685;CS-O-31011;delta1-Cortisone;PREDNISONE (USP-RS);Q424972;Retrocortine;GB/T 24800.2-2009 41 Glucocorticoids 100 microg/mL in Methanol;MLS002154191;NCGC00090766-03;In-Sone;.delta.1-Cortisone;Meticorten (TN);53-03-2;P1276;Prednisonum (Latin);Prednicen-M;Tox21_111014_1;Deltisona;PREDNISONE [EP MONOGRAPH];1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione;Predicorten;NCGC00090766-01;Prednisone (Adasone);Prednison;Predniment;Pred;NCGC00259113-01;Origen Prednisone;Precort;Perrigo Prednisone;NCGC00254096-01;Kortancyl;SMR000718760;NCGC00090766-07;Lodtra;DTXCID701185;Dellacort A;Pehacort;Me-Korti;Prednisone [USP:INN:BAN];delta1-Dehydrocortisone;PREDNISONE (USP MONOGRAPH);SCHEMBL3288;LMST02030180;Delta-Dome;(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione;17alpha,21-dihydroxypregna-1,4-diene-3,11,20-trione;Prestwick_405;1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione;Zenadrid [veterinary];NSC10023;1, 2-Dehydrocortisone;HY-B0214;BRD-K85883481-001-04-2;(1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11a...
Cas No.	53-03-2
分子式	C₂₁H₂₆O₅
分子量	358.43
包装储存	Powder -20°C 3 years；4°C 2 years

产品详情

Prednisone (Adasone) 是皮质类固醇试剂，具有抗炎及免疫抑制作用，可用于研究系统性红斑狼疮等相关疾病。

生物活性

Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus.

性状

Solid

体内研究(In Vivo)

Prednisone (intramuscular injection, 10 mg/kg once a day, on days 4 to 13) reduces the survival rate on days lower than the control group in BALB/c mice with encephalomyocarditis virus myocarditis. Besides, myocardial virus titers reaches a maximum on day 4, but there is no antibody titer, and on day 8 virus titers remains elevated and antibody titers is also high. On day 10, antibody titers are significantly lower than controls, while viral titers remains significantly elevated.
Prednisone (5 mg/kg, intragastrically administration, daily) can cause changes in FA metabolism in SLE mouse (MRL/lpr) model.
has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder -20°C 3 years；4°C 2 years

ClinicalTrial

参考文献

[1]. RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1(4):488-96.
[2]. [2]N Tomioka, et al. Effects of prednisolone on acute viral myocarditis in mice. J Am Coll Cardiol. 1986 Apr;7(4):868-72.
[3]. Qianqian Li, et al. Metabolic Profiling Rev

溶解度数据	In Vitro: DMSO : 125 mg/mL (348.74 mM; ultrasonic and warming and heat to 80°C)H₂O : 1 mg/mL (2.79 mM; ultrasonic and warming and heat to 80°C)

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Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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