Mal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.
性状
Solid
IC50 & Target[1][2]
Daunorubicins/Doxorubicins
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
-20°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献
[1]. Brian Lannutti,et al. Ror1 antibody immunoconjugates. WO2018237335A1.