Mal-VC-PAB-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB .
性状
Solid
IC50 & Target[1][2]
Maytansinoids
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献
[1]. Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.
溶解度数据
In Vitro: DMSO : 75 mg/mL (60.06 mM; Need ultrasonic)配制储备液