SuO-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide SuO-Val-Cit-PAB.
性状
Solid
IC50 & Target[1][2]
Auristatin
体外研究(In Vitro)
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
-80°C, stored under nitrogen 该产品在溶液状态不稳定,建议您现用现配,即刻使用。
参考文献
[1]. Kamath AV, et al. Preclinical Pharmacokinetic Considerations for the Development of Antibody Drug Conjugates. Pharm Res. 2015 Nov;32(11):3470-9.