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甲状旁腺激素相关蛋白(PTHrP)重组蛋白
目录号: PC22037 纯度: >97%
商品编号 规格 价格 会员价 是否有货 数量
PC22037-10ug 10ug ¥1123.00 请登录
PC22037-50ug 50ug ¥2808.00 请登录
PC22037-200ug 200ug ¥5616.00 请登录
PC22037-1mg 1mg ¥16848.00 请登录
Medlife所售产品仅用于科学研究(非临床研究),非药品不可食用,不可用于人体或动物的临床诊断和治疗,我们不为个人提供产品及服务。产品COA等资料,可至下方“质量控制”中下载。
中文名称
甲状旁腺激素相关蛋白(PTHrP)重组蛋白
包装储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
产品详情
内毒素水平:<1.0EU/µg(LAL法测定) 片段与标签:Ala37~His177 with N-terminal His Tag 缓冲液成份:20mM Tris, 150mM NaCl缓冲液(pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300) 亚细胞定位:细胞核, 分泌, 细胞质 应用:Positive Control; Immunogen; SDS-PAGE; WB. 用法:Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
生物活性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
性状
冻干粉
运输条件
冷藏运输。
储存方式
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
来源
原核表达,宿主E.coli
参考文献
Clinical and Experimental Metastasis:Characterization of a new renal cell carcinoma bone metastasis mouse model [PubMed: 20443133] Stem Cells and Development:Temporal activation of β-catenin signaling in the chondrogenic process of mesenchymal stem cells affects the phenotype of the cartilage generated. [PubMed: 22133004] International journal of biological sciences:PTHrP Expression in Human MDA-MB-231 Breast Cancer Cells Is Critical for Tumor Growth and Survival and Osteoblast Inhibition [PubMed: PMC3753447] Investigational New Drugs:Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts [Pubmed: 23673814] Toxicology and Applied Pharmacology:Betulinic acid, a bioactive pentacyclic triterpenoid, inhibits skeletal-related events induced by breast cancer bone metastases and treatment [Pubmed:24463094] Arch Gynecol Obstet.:Calcitonin gene-and parathyroid hormone-related peptides in normotensive and preeclamptic pregnancies: a nested case–control study [Pubmed:24943060] PLoS One:15-Deoxy-Δ12, 14-Prostaglandin J2 Inhibits Osteolytic Breast Cancer Bone Metastasis and Estrogen Deficiency-Induced Bone Loss [PubMed: 25859665] Endocrinology:A role for the calcitonin receptor to limit bone loss during lactation in female mice by inhibiting osteocytic osteolysis [PubMed: 26135836] Tumour Biol:Osteopontin expression in co-cultures of human squamous cell carcinoma-derived cells and osteoblastic cells and its effects on the neoplastic cell phenotype and osteoclastic activation. [Pubmed:27312487] 35:Hedgehog signaling in bone regulates whole-body energy metabolism through a bone–adipose endocrine relay mediated by PTHrP and adiponectin [pubmed:27740628] Bone:Lactation induces increases in the RANK/RANKL/OPG system in maxillary bone [Pubmed:29382610] International Journal of Molecular Sciences:A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice [Pubmed: 31600911] Journal of Orthopaedic Surgery and Research:Identification of a potential gene target for osteoarthritis based on bioinformatics analyses [Pubmed: 32571421] International Immunopharmacology:Parathyroid hormone related protein (PTHrP)-mediated hypercalcemia in malignancy associated with anti-PD-1 immune checkpoint inhibitor treatment and related … [] Паратиреоидный гормон-родственный протеин как предиктор развития мочекаменной болезни [] Cell Death Dis:Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer ¡­ [33510128] Sci Rep:Effects of whole-body vibration training in a cachectic C26 mouse model [34732809] Acta Physiologica:The acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals [Pubmed:35334154]
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2