内毒素水平:<1.0EU/µg(LAL法测定)
片段与标签:Ala37~His177 with N-terminal His Tag
缓冲液成份:20mM Tris, 150mM NaCl缓冲液(pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300)
亚细胞定位:细胞核, 分泌, 细胞质
应用:Positive Control; Immunogen; SDS-PAGE; WB.
用法:Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Clinical and Experimental Metastasis:Characterization of a new renal cell carcinoma bone metastasis mouse model [PubMed: 20443133]
Stem Cells and Development:Temporal activation of β-catenin signaling in the chondrogenic process of mesenchymal stem cells affects the phenotype of the cartilage generated. [PubMed: 22133004]
International journal of biological sciences:PTHrP Expression in Human MDA-MB-231 Breast Cancer Cells Is Critical for Tumor Growth and Survival and Osteoblast Inhibition [PubMed: PMC3753447]
Investigational New Drugs:Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts [Pubmed: 23673814]
Toxicology and Applied Pharmacology:Betulinic acid, a bioactive pentacyclic triterpenoid, inhibits skeletal-related events induced by breast cancer bone metastases and treatment [Pubmed:24463094]
Arch Gynecol Obstet.:Calcitonin gene-and parathyroid hormone-related peptides in normotensive and preeclamptic pregnancies: a nested case–control study [Pubmed:24943060]
PLoS One:15-Deoxy-Δ12, 14-Prostaglandin J2 Inhibits Osteolytic Breast Cancer Bone Metastasis and Estrogen Deficiency-Induced Bone Loss [PubMed: 25859665]
Endocrinology:A role for the calcitonin receptor to limit bone loss during lactation in female mice by inhibiting osteocytic osteolysis [PubMed: 26135836]
Tumour Biol:Osteopontin expression in co-cultures of human squamous cell carcinoma-derived cells and osteoblastic cells and its effects on the neoplastic cell phenotype and osteoclastic activation. [Pubmed:27312487]
35:Hedgehog signaling in bone regulates whole-body energy metabolism through a bone–adipose endocrine relay mediated by PTHrP and adiponectin [pubmed:27740628]
Bone:Lactation induces increases in the RANK/RANKL/OPG system in maxillary bone [Pubmed:29382610]
International Journal of Molecular Sciences:A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice [Pubmed: 31600911]
Journal of Orthopaedic Surgery and Research:Identification of a potential gene target for osteoarthritis based on bioinformatics analyses [Pubmed: 32571421]
International Immunopharmacology:Parathyroid hormone related protein (PTHrP)-mediated hypercalcemia in malignancy associated with anti-PD-1 immune checkpoint inhibitor treatment and related … []
Паратиреоидный гормон-родственный протеин как предиктор развития мочекаменной болезни []
Cell Death Dis:Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer ¡ [33510128]
Sci Rep:Effects of whole-body vibration training in a cachectic C26 mouse model [34732809]
Acta Physiologica:The acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals [Pubmed:35334154]