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Hypoxanthine

(Synonyms: 次黄嘌呤; Purin-6-ol; Sarcine)

目录号: PC61703 纯度: ≥99%

Hypoxanthine 是嘌呤衍生物，也是一种潜在的自由基发生器，可以作为缺氧指征的指示剂。Hypoxanthine 是嘌呤衍生物，也是一种潜在的自由基发生器，可以作为缺氧指征的指示剂。

CAS No. :68-94-0

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中文名称	Hypoxanthine
中文别名	次黄嘌呤;6-羟基嘌呤;1,7-二氢-6H-嘌呤-6-酮;6-羟基嘌呤(次黄嘌呤);6-氧嘌呤;次黄碱;6-羥嘌呤;6-次黃嘌呤;嘌呤-6(1H)-酮;6-Hydroxypurine 次黄嘌呤标准品;6-羟基嘌呤,6-Hydroxypurine;6-羟基嘌呤标准品;Hypoxanthine 次黄嘌呤;次黄嘌呤,BR;次黄嘌呤、6-羟基嘌呤;次黄嘌呤标准品;地达诺辛杂质A;地达诺新杂质A EP标准品;地达诺新杂质A标准品;地丹诺辛相关物质A USP标准品;去羟肌苷杂质A;次黄碱,6-氧嘌呤,6-羟基嘌呤;次黄嘌呤(6-羟基嘌呤,6-羟基嘌呤,次黄碱)
英文名称	Hypoxanthine
英文别名	1H-Purin-6(9H)-one;1,7-DIHYDRO-6H-PURIN-6-ONE;6(1H)-PURINONE;6-HYDROXYPURINE;9H-PURIN-6-OL;IFLAB-BB F1386-0269;Purin-6(1H)-one;PURIN-6-OL;SARCINE;SARKIN;TIMTEC-BB SBB004203;TTGGTTGGGTGGTHGGTGTTGGGG;1,7-dihydro-6h-purin-6-on;1,7-Dihydro-6H-purine-6-one;3H-Purin-6-ol;4-Hydroxy-1H-purine;6H-Purin-6-one, 1,7-dihydro-;6-Hydropurine;Hypoxanthine;HYPOXANTHINE(RG);Hypoxsanthine (1,7-Dihydro-6H-purin-6-one);1,7-dihydro-purin-6-one;6-Oxopurine;6-oxypurine;Hypexanthine;Hypoxanthin;Hypoxathine;Purine-6 (1H)-one;Purine-6-ol;Sarkine;Hypoxanthine enol;7H-Purin-6-ol;9H-Purin-6(1H)-one;Purin-6(3H)-one;6-Hydroxy-1H-purine;9H-Purin-6-ol (VAN);6H-Purin-6-one, 1,9-dihydro-;1,9-dihydro-6H-purin-6-one;3,7-dihydropurin-6-one;3H-Purin-6-ol (9CI);1H-Purin-6-ol (9CI);6,7-di
Cas No.	68-94-0
分子式	C₅H₄N₄O
分子量	136.11
包装储存	Powder； -20°C； 3 years; 4°C； 2 years；
详情描述	Hypoxanthine 是嘌呤衍生物，也是一种潜在的自由基发生器，可以作为缺氧指征的指示剂。Hypoxanthine 是嘌呤衍生物，也是一种潜在的自由基发生器，可以作为缺氧指征的指示剂。

生物活性	Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
性状	Solid
IC50 & Target[1][2]	Human Endogenous Metabolite Microbial Metabolite
体外研究(In Vitro)	Hypoxanthine is a potential free radical generator. Hypoxanthine seems to play a role in posthypoxic reoxygenation cell injury through oxygen radical production and is therefore involved in the pathogenesis of a number of diseases. Hypoxanthine also modulates a number of other processes because it reacts with benzodiazepine receptors and inhibits phosphodiesterase in the brain. Hypoxanthine inhibits the effect of several cytotoxic drugs and may therefore influence treatment with such drugs.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	In pigs, a linear increase of plasma hypoxanthine with duration of hypoxemia is found, and there is no difference between arterial and venous plasma. There are good correlations between hypoxanthine and lactate, base deficit and pH. There is also a direct relationship between survival time and increase in plasma hypoxanthine. Survival time correlates negatively with the rate of hypoxanthine increase (r=-0.62).All animals die when hypoxanthine exceeds 125 pM/liter. The increase of hypoxanthine therefore reflected the prognosis of acute hypoxia in contrast to base deficit.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature or refrigerated transport.
储存方式	Powder； -20°C； 3 years; 4°C； 2 years；
结构分类	Others

溶解度数据	体外研究: DMSO : 10 mg/mL(73.47 mM;Need ultrasonic) 配制储存液

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Hypoxanthine

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