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25,26-Dihydroxyvitamin D3

(Synonyms: 25,26-Dihydroxycholecalciferol)

目录号: PC62145 纯度: ≥98%

25,26-Dihydroxyvitamin D3是维生素D3代谢物。25,26-Dihydroxyvitamin D3是维生素D3代谢物。

CAS No. :29261-12-9

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中文名称	25,26-Dihydroxyvitamin D3
中文别名	25,26-二羟基维生素d3;三裂鼠尾草素;25,26二羟基维生素D3;25,26-二羟基维他命 D3
英文名称	25,26-Dihydroxyvitamin D3
英文别名	9,10-Secocholesta-5,7,10(19)-triene-3,25,26-triol,(3b,5Z,7E)- (9CI);25,26-Dihydroxy Vitamin D3;25,26-Dihydroxycholecalciferol;(5E,7E)-9,10-Secocholesta-5,7,10-triene-3,25,26-triol;25,26-Dihydroxyvitamin D;25,26-Dihydroxyvitamin D3
Cas No.	29261-12-9
分子式	C₂₇H₄₄O₃
分子量	416.64
包装储存	4°C, Keep In Dark, stored under nitrogen；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark, stored under nitrogen)；
详情描述	25,26-Dihydroxyvitamin D3是维生素D3代谢物。25,26-Dihydroxyvitamin D3是维生素D3代谢物。

生物活性	25,26-Dihydroxyvitamin D3(25,26-dihydroxycholecalciferol) is a metabolite of vitamin D3 with intestinal calcium transport activity.IC50 value:Target: VD metaboliteThe biological activity of synthetic 24,25 and 25,26 diOHD3 was studied in vitamin D-deficient rats. The purpose of this study was to investigate the influence of small doses of both metabolites (0.125-0.250 mug) upon intestinal calcium transport and bone calcium mobilization. Both metabolites were able to increase calcium absorption in rats maintained on a calcium-deficient diet, but failed to do it in rats on a normal calcium diet. Bilateral nephrectomy suppressed this effect. The "bone calcium mobilization" of both derivatives was measured in vitamin D and calcium- or phosphorus-deprived rats after one intravenous dose. When serum calcium was initially low, 24,25 and 25,26 diOHD3 increased serum calcium moderately, but the increment was only significa
性状	Solid
IC50 & Target[1][2]	Human Endogenous Metabolite

运输条件

Room temperature or refrigerated transport.

储存方式

4°C, Keep In Dark, stored under nitrogen；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark, stored under nitrogen)；

结构分类

Others

溶解度数据	体外研究: DMSO : 100 mg/mL(240.02 mM;Need ultrasonic) 配制储存液

搜索质检报告(COA)

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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