Thevetiaflavone|29376-68-9|(Apigenin-5-methyl ether)-陌孚医药/Medlife

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Thevetiaflavone (Synonyms: Apigenin-5-methyl ether)

目录号: PC59139 纯度: ≥98.0%

CAS No. :29376-68-9

商品编号	规格	价格	会员价	是否有货	数量
PC59139-1mg	1mg	询价	询价

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中文名称	Thevetiaflavone
中文别名	黄花夹竹桃黄酮;对照品;黄花夹竹桃黄酮标准品
英文名称	Thevetiaflavone
英文别名	4H-1-Benzopyran-4-one,7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-;ethyl prop-2-enoate, 2-methylprop-2-enoic acid, propane-1,2-diol, styrene;Thevetiaflavone;5,4'-Dimethoxy-7-hydroxy-flavon;5-Methoxy-7,4'-dihydroxyflavon;5-methoxy-7,4'-dihydroxyflavone;5-O-methylacacetin;7,4'-dihydroxy-5-methoxy-flavone;7-Hydroxy-5,4'-dimethoxy-isoflavon;apigenin 4',5-dimethyl ether;apigenin 5,4'-dimethyl ether;apigenin 5-monomethyl ether;Apigenin 5-O-monomethyl ether;Apigenin-5-methyl ether;4',7-Dihydroxy-5-methoxyflavone;[ "" ]
Cas No.	29376-68-9
分子式	C₁₆H₁₂O₅
分子量	284.26
包装储存	4°C, Keep In Dark；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark)；

生物活性	Thevetiaflavone could upregulate the expression of Bcl?2 and downregulate that of Bax and caspase?3.
性状	Solid
IC50 & Target[1][2]	Bcl-2 Bax
体外研究(In Vitro)	Thevetiaflavone, a natural flavonoid obtained from Wikstroemia indica, could improve cell viability and suppresses the leakage of lactate dehydrogenase from the cytoplasm. Further investigation of the mechanisms demonstrated that Thevetiaflavone decreases overproduction of ROS and ameliorates ROS?mediated mitochondrial dysfunction, including collapse of mitochondrial membrane potential and mitochondrial permeability transition pore opening. Thevetiaflavone reduces the intracellular Ca level, which is closely associated with mitochondrial function and interplays with ROS. Furthermore, Thevetiaflavone inhibits apoptosis in PC12 cells through upregulating the expression of Bcl?2 and downregulating that of Bax and caspase?3 in addition to increasing the activity of caspase?3. These results further indicate the protective effects of thevetiaflavone in vivo and its application in th
运输条件	Room temperature or refrigerated transport.
储存方式	4°C, Keep In Dark；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark)；
结构分类	Flavonoids Flavon
来源	Plants other fami

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2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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