Convallatoxin|508-75-8|(铃兰毒苷)-陌孚医药/Medlife

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Convallatoxin (Synonyms: 铃兰毒苷)

目录号: PC64455 纯度: ≥98%

CAS No. :508-75-8

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中文名称	Convallatoxin
中文别名	铃兰毒甙;铃兰毒苷;K-毒毛旋花子配质-3-L-鼠李糖甙;鈴蘭毒;君影草毒素;铃兰毒
英文名称	Convallatoxin
英文别名	Card-20(22)-enolide,3-[(6-deoxy-a-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-,(3b,5b)-;Convallatoxin;CONVALLATOXIN(P);CONVALLATOXIN(RG);3β,5α,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide 3-(6-deoxy-α-L-mannopyranoside);Strophanthidin α-L-rhamnopyranoside;convallaotoxin;convallaton;convallatoxoside;convallotoxin;corglycon;corglycone;corglykon;orglycon;Korglykon;NSC 407808;Strophanthidin alpha-L-rhamnoside;Strophanthidin 3-O-alpha-L-rhamnoside;Strophanthidin, 3-(6-deoxy-alpha-L-mannopyranoside);JY264VIR1Y;Convallopan;Convalpur;Convapur;Strophanthidin alpha-L-rha
Cas No.	508-75-8
分子式	C₂₉H₄₂O₁₀
分子量	550.64
包装储存	4°C, Keep In Dark；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark)；

生物活性	Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved in its transport. Convallatoxin is an enhancer of ligand-induced MOR endocytosis with high potency and efficacy. Anti-inflammatory and anti-proliferative properties.
性状	Solid
体外研究(In Vitro)	Convallatoxin induces HaCaT cell necroptosis.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	Convallatoxin exerts antipsoriatic activities in two mouse models of psoriasis.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature or refrigerated transport.
储存方式	4°C, Keep In Dark；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark)；
结构分类	Terpenoids Triter
来源	Plants

溶解度数据	体外研究: DMSO : 50 mg/mL(90.80 mM;Need ultrasonic) 配制储存液

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