您当前的位置：

Catechin

(Synonyms: 儿茶素; (+)-Catechin; Cianidanol; Catechuic acid)

目录号: PC58269 纯度: ≥99%

Catechin ((+)-Catechin) 抑制环加氧酶-1 (COX-1) , IC50 为 1.4 μM。Catechin ((+)-Catechin) 抑制环加氧酶-1 (COX-1) , IC50 为 1.4 μM。

CAS No. :154-23-4

商品编号	规格	价格	会员价
PC58269-10mg	10mg	¥741.00	请登录
PC58269-50mg	50mg	¥1111.00	请登录
PC58269-100mg	100mg	¥1729.00	请登录

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Catechin
中文别名	儿茶精;羟黄酮;儿茶素分析对照品;(+)-儿茶素;右旋儿茶酚;(2R-反)-2-(3,4-二羟苯基)-3,4-二氢-2H-苯并吡喃-3,5,7-三醇(酚);西阿尼醇;(2R,3S)-2-(3,4-二羟基苯基)-3,4-二氢-2H-苯并吡喃-3,5,7-三醇;(+)-儿茶精水合物;(+)-儿茶素, 来源于绿茶;(+)-儿茶酸 USP标准品;:(+)儿茶素;儿茶精,绿茶提取物[绿茶];儿茶素植物提取物,标准品,对照品;儿茶酸;绿茶提取物;(+)儿茶素;(+)-儿茶素水合物;((+)儿茶素;茶单宁;儿茶酚;儿茶素;邻苯二酚;邻苯二酚,羟黄酮;儿茶精,儿茶素;儿茶素,儿茶精
英文名称	Catechin
英文别名	(+)-catechin;(2R,3S)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol;CATECHIN;CATECHIN, (+)-;D-CATECHIN;(+)-3,3'4',5,7-FLAVANEPENTOL;3,3',4',5,7-PENTAHYDROXYFLAVANE;[2R,3S]-2-[3,4-DIHYDROXYPHENYL]-3,4-DIHYDRO-1[2H]-BENZOPYRAN-3,4,7-TRIOL;2-(3,4-dihydroxyphenyl)-3,4-dihydro-(2r-trans)-2h-1-benzopyran-7-triol;Cianidanol;(+)-Catechin Hydrate;3,3',4',5,7-FLAVANPENTOL;CATECHIN, (+)-(P) (AHP Verified) (REQUEST QUOTE);CATECHIN, (+)-(P) (AHP Verified) (REQUEST QUOTE) PrintBack;(+)-3,3,4,5,7-Flavanpentol;(+)-3,3',4',5,7-Flavanpentol Hydrate;3-Cyanidanol, (+)-;Catechuic acid;Cyanidanol;Catechin（C）;(+)-Cyanidanol;(2R,3S)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol;kb-53;catergen;(2R,3S)-;d-catechol;Drenoliver;[ "" ];(-)-Epicatechin;Epicatechin;L-Epicatechin;(-)-Epicatechol;l-Acacatechin;(-)epicatechin;(2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol;Epicatechol;l-Epicatechol;epi-Catechin;(2R,3R)-(-)-Epicatechin;epi-Catechol;Epicatechol, (-)-;34PHS7TU43;PFTAWBLQPZVEMU-UKRRQHHQSA-N;(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol;(-)-(2R:3R)-5,7,3',4'-Tetrahydroxyflavan-3-ol;(-)-cis-Epicatechin;C15H14O6;2-(3,4-Dihydro
Cas No.	154-23-4
分子式	C₁₅H₁₄O₆
分子量	290.27
包装储存	4°C, Sealed and stored away from moisture and light；*In solvent : -80°C, 6 months; -20°C, 1 month (Sealed and stored away from moisture and light)；
详情描述	Catechin ((+)-Catechin) 抑制环加氧酶-1 (COX-1) , IC50 为 1.4 μM。Catechin ((+)-Catechin) 抑制环加氧酶-1 (COX-1) , IC50 为 1.4 μM。

生物活性

Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC₅₀ of 1.4 μM.

性状

Solid

IC50 & Target[1][2]

COX-1
1.4 μM (IC50)Human Endogenous Metabolite

体外研究(In Vitro)

Catechin ((+)-Catechin) exhibits >95% inhibitory activity at 70 μg/mL against cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
A dose-dependent reduction in color is observed after 24 hours of treatment with Catechin, and 54.76% of the cells are dead at the highest concentration of Catechin tested (160 μg/mL) whereas the IC50 of Catechin is achieved at 127.62 μg/mL Catechin. A dose- and time-dependent increase in the induction of apoptosis is observed when MCF-7 cells are treated with Catechin. When compare to the control cells at 24 hours, 40.7 and 41.16% of the cells treated with 150 μg/mL and 300 μg/mL Catechin, respectively, undergo apoptosis. The expression levels of Caspase-3, -8, and -9 and p53 in MCF-7 cells treated with 150 μg/mL Catechin for 24 h increase by 5.81, 1.42, 3.29, and 2.68 fold, respectively, as co

体内研究(In Vivo)

Animals treated with Catechin ((+)-Catechin) at the lowest tested dose, i.e., 50 mg/kg, p.o. have spent comparatively more time in exploring the novel object in the choice trial, however, the difference is not statistically significant. Catechin prevents the time-induced episodic memory deficits in a dose-dependent manner, the most effective being 200 mg/kg, p.o.. Treatment with Catechin prevents the rise in MPO level compare to DOX alone treatment group (21.98±9.44 and 36.76±4.39% in the hippocampus and the frontal cortex respectively).Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature or refrigerated transport.

储存方式

4°C, Sealed and stored away from moisture and light；*In solvent : -80°C, 6 months; -20°C, 1 month (Sealed and stored away from moisture and light)；

ClinicalTrial

结构分类

Flavonoids
Flavan

来源

Plants

溶解度数据	体外研究: DMSO : ≥ 100 mg/mL(344.51 mM) H₂O : 12.5 mg/mL(43.06 mM;Need ultrasonic) *≥ means soluble, but saturation unknown.

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

Catechin

相关产品

The molarity calculator equation

The dilution calculator equation